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Friday, November 30, 2007

Science, Vol 318, Issue 5854, Pages 1213-1318

Shape and Temperature Memory of Nanocomposites with Broadened Glass Transition
Pierre Miaudet, Alain Derré, Maryse Maugey, Cécile Zakri, Patrick M. Piccione, Rabi Inoubli, and Philippe Poulin
pg. 1294-1296

Biomaterials, Volume 29, Issue 3-5, Pages 257-624 (January-February 2008)

The rheological properties of silated hydroxypropylmethylcellulose tissue engineering matrices
Pages 533-543
Ahmed Fatimi, Jean François Tassin, Sophie Quillard, Monique A.V. Axelos and Pierre Weiss

Strong biofilm production, antibiotic multi-resistance and high gelE expression in epidemic clones of Enterococcus faecalis from orthopaedic implant infections
Pages 580-586
Carla Renata Arciola, Lucilla Baldassarri, Davide Campoccia, Roberta Creti, Valter Pirini, Johannes Huebner and Lucio Montanaro

An injectable cross-linked scaffold for nucleus pulposus regeneration
Pages 438-447
Damien O. Halloran, Sibylle Grad, Martin Stoddart, Peter Dockery, Mauro Alini and Abhay S. Pandit

Biotinylated thermoresponsive micelle self-assembled from double-hydrophilic block copolymer for drug delivery and tumor target
Pages 497-505
Cheng Cheng, Hua Wei, Bao-Xian Shi, Han Cheng, Cao Li, Zhong-Wei Gu, Si-Xue Cheng, Xian-Zheng Zhang and Ren-Xi Zhuo

A thermoreversible hydrogel as a biosynthetic bandage for corneal wound repair
Pages 272-281
Chayanin Pratoomsoot, Hidetoshi Tanioka, Kuniko Hori, Satoshi Kawasaki, Shigeru Kinoshita, Patrick J. Tighe, Harminder Dua, Kevin M. Shakesheff and Felicity Rosamari A.J. Rose

Assessment of stem cell/biomaterial combinations for stem cell-based tissue engineering
Pages 302-313
Sabine Neuss, Christian Apel, Patricia Buttler, Bernd Denecke, Anandhan Dhanasingh, Xiaolei Ding, Dirk Grafahrend, Andreas Groger, Karsten Hemmrich, Alexander Herr, Willi Jahnen-Dechent, Svetlana Mastitskaya, Alberto Perez-Bouza, Stephanie Rosewick, Jochen Salber, Michael Wöltje and Martin Zenke

The effect of enzymatically degradable poly(ethylene glycol) hydrogels on smooth muscle cell phenotype
Pages 314-326
Catharina Adelöw, Tatiana Segura, Jeffrey A. Hubbell and Peter Frey

Wednesday, November 21, 2007

ACS Chemical Biology, vol. 2, iss. 11 (Nov. 20, 2007)

pg. 715
James T. Hodgkinson, Martin Welch, and David R. Spring

JACS Vol. 129, No. 47 (Nov. 28, 2007)

.
Supramolecular Star Polymers. Increased Molecular Weight with Decreased Polydispersity through Self-Assembly

pp 14534 - 14535
Eric M. Todd and Steven C. Zimmerman



Tuning the Thermoresponsiveness of Weak Polyelectrolytes by pH and Light: Lower and Upper Critical-Solution Temperature of Poly(N,N-dimethylaminoethyl methacrylate)
pp 14538 - 14539
Felix A. Plamper, Alexander Schmalz, Matthias Ballauff, and Axel H.E. Müller

Intrinsically Cell-Permeable Miniature Proteins Based on a Minimal Cationic PPII Motif
pp 14578 - 14579
Douglas S. Daniels and Alanna Schepartz

Real-Time Observation of Polyelectrolyte-Induced Binding of Charged Bilayers
pp 14619 - 14624
Yuxia Luan and Laurence Ramos


D-Periodic Collagen-Mimetic Microfibers

pp 14780 - 14787
Shyam Rele, Yuhua Song, Robert P. Apkarian, Zheng Qu, Vincent P. Conticello, and Elliot L. Chaikof



Inherent Antibacterial Activity of a Peptide-Based beta-Hairpin Hydrogel
pp 14793 - 1479

Daphne A. Salick, Juliana K. Kretsinger, Darrin J. Pochan, and Joel P. Schneider

JACS Vol. 129, No. 46 (Nov. 21, 2007)

.
Biomimetic Design of Reversibly Unfolding Cross-Linker to Enhance Mechanical Properties of 3D Network Polymers

pp 14110 - 14111
Aaron M. Kushner, Vahe Gabuchian, Evan G. Johnson, and Zhibin Guan

Facile RAFT Precipitation Polymerization for the Microwave-Assisted Synthesis of Well-Defined, Double Hydrophilic Block Copolymers and Nanostructured Hydrogels
pp 14493 - 14499
Zesheng An, Qihui Shi, Wei Tang, Chia-Kuang Tsung, Craig J. Hawker, and Galen D. Stucky

JACS Vol. 129, No. 45, (Nov. 14, 2007)

.
Mechanophore-Linked Addition Polymers
pp 13808 - 13809
Stephanie L. Potisek, Douglas A. Davis, Nancy R. Sottos, Scott R. White, and Jeffrey S. Moore

Fluorescently Labeled Cellulose Nanocrystals for Bioimaging Applications
pp 13810 - 13811
Shuping Dong and Maren Roman

Self-Assembled Templates for Polypeptide Synthesis

pp 14074 - 14081
Maxim G. Ryadnov and Derek N. Woolfson

Friday, November 16, 2007

Monday, November 5, 2007

Biotechnology Progress (Volume: 23, 6 issues)


Makoto Yoshimoto, Miyuki Monden, Zhongwei Jiang, and Katsumi Nakao

Biotechnology Progress (Volume: 23, 6 issues)




Akiyoshi Hoshino, Noriyuki Ohnishi, Masato Yasuhara, Kenji Yamamoto, and Akihiko Kondo

ChemBioChem 2007, 8, 1850 – 1856

Tripeptides from Synthetic Amino Acids Block the Tat–TAR Association and Slow Down HIV Spread in Cell Cultures

Verena Ludwig,[a] Andreas Krebs,[a] Michaela Stoll,[b] Ursula Dietrich,[b]
Jan Ferner,[a] Harald Schwalbe,[a] Ute Scheffer,[a] Gerd D!rner,[a] and
Michael W. Gçbel*[a]

Organic Letters, 2007, 9, 4311

Convergent Synthesis of a Fully Phosphorylated GPI Anchor of the CD52 Antigen
Xiaoming Wu and Zhongwu Guo*


anoyher very complex sugar protection and deprotection

Organic Letters, 2007, 9, 4631

Helical Chirality Transmission through a p-Phenylene Fragment in a Hexa-ì5-phosphazene
Mateo Alajarı´n,* Carmen Lo´ pez-Leonardo, and Jose´ Berna



Organic Letters, 2007, 9, 4515

Selectively Chemodosimetric Detection of Hg(II) in Aqueous Media
Min Hee Lee,† Byoung-Ki Cho,† Juyoung Yoon,‡ and Jong Seung Kim*,§


A Hg2+ sensor

Organic Letters, 2007, 9, 4415

Synthesis of a Neamine Dimer Targeting the Dimerization Initiation Site of HIV-1 RNA

Anne Bodlenner,† Aure´lien Alix,† Jean-Marc Weibel,† Patrick Pale,*,† Eric Ennifar,‡
Jean-Christophe Paillart,‡ Philippe Walter,‡ Roland Marquet,‡ and
Philippe Dumas‡



This paper shows their ability to protect and deprotect the sugar

Org. Biomol. Chem., 2007, 5, 3535 - 3538

Thiourea-based molecular clips for fluorescent discrimination of isomeric dicarboxylates
Zhi-hua Lin, Li-xia Xie, Yong-gang Zhao, Chun-ying Duan and Jing-ping Qu

Org. Biomol. Chem., 2007, 5, 3577 - 3585


Design and synthesis of -helical peptides and mimetics
James Garner and Margaret M. Harding

PNIPAAM-Modified Nanoporous Colloidal Films with Positive and

Olga Schepelina and Ilya Zharov*

Langmuir, ASAP

Self-assembly of metal–polymer analogues

ZHIHONG NIE1, DANIELE FAVA1, EUGENIA KUMACHEVA*, SHAN ZOU, GILBERT C. WALKER, AND MICHAEL RUBINSTEIN

nature materials VOL 6, AUGUST 2007, p609

Electrochemically assisted self-assembly of

nature materials VOL 6, AUGUST 2007, p602.

Interfaces behaving well

nature materials VOL 6, AUGUST 2007, 551.

Tastes good to me

nature materials VOL 6 , AUGUST 2007, p548.

Nano Letters, Vol. 7, Iss. 10, October 2007.

Fluorescence Probes for Membrane Potentials Based on Mesoscopic Electron Transfer

Liang-shi Li, pp 2981 - 2986.


Advances in Polymer Science, Volume 220, 2007.

Synthesis of Stimuli-Responsive Polymers by Living Polymerization: Poly( N -Isopropylacrylamide) and Poly(Vinyl Ether)s

Sadahito Aoshima and Shokyoku Kanaoka, p. 169-208.

JACS Vol. 129, No. 43 (Oct 31, 2007)

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Cylindrical Block Co-Micelles with Spatially Selective Functionalization by Nanoparticles
pp 12924 - 12925
Hai Wang, Wanjuan Lin, Karolina P. Fritz, Gregory D. Scholes, Mitchell A. Winnik, and Ian Manners


Programmed Thermodynamic Formation and Structure Analysis of Star-like Nanogels with Core Cross-linked by Thermally Exchangeable Dynamic Covalent Bonds
pp 13298 - 13304
Yoshifumi Amamoto, Yuji Higaki, Yasuhiro Matsuda, Hid
eyuki Otsuka, and Atsushi Takahara



A Peptide Dendrimer Enzyme Model with a Single Catalytic Site at the Core
pp 13238 - 13246
Sacha Javor, Estelle Delort, Tamis Darbre, and Jean-Louis Reymond

Macromolecules, Vol. 40, No. 22, 2007

Templating Conducting Polymers via Self-Assembly of Block Copolymers and Supramolecular
Recognition


Lynne A. McCullough, Bruno Dufour, Chuanbing Tang,Rui Zhang, Tomasz Kowalewski, and
Krzysztof Matyjaszewski

Advanced Materials 2007, 19, 3171–3176

Quantifying the Performance of Protein-Resisting Surfaces at Ultra-Low Protein Coverages using Kinesin Motor Proteins as Probes

By Parag Katira, Ashutosh Agarwal, Thorsten Fischer, Hsien-Yeh Chen, Xuwei Jiang, Joerg Lahann, and Henry Hess

Nature Reviews Microbiology 2007, 5(11), p833.

In a Class of Their Own

Sheilagh Molloy

ORIGINAL RESEARCH PAPER
Swe, P. M. et al. ef1097 and ypkK encode enterococcin V583 and corynicin JK, members of a new family of antimicrobial proteins (bacteriocins) with modular structure from Gram-positive bacteria. Microbiology 153, 3218–3227 (2007)

Antimicrobial Agents and Chemotherapy 2007, 51(11), pp 4148-4156

Antimicrobial Effect of Halocidin-Derived Peptide in a Mouse Model of Listeria Infection

Woong Sik Jang, Sang-Chul Lee, Young Shin Lee, Yong Pyo Shin, Kyoung Hwa Shin, Boo Hee Sung, Byung S. Kim, Soo Han Lee, and In Hee Lee

Antimicrobial Agents and Chemotherapy 2007, 51(11), pp. 4125-4132

Activity of an Antimicrobial Peptide Mimetic against Planktonic and Biofilm Cultures of Oral Pathogens

Nicholas Beckloff, Danielle Laube, Tammy Castro, David Furgang, Steven Park, David Perlin, Dylan Clements, Haizhong Tang, Richard W. Scott, Gregory N. Tew, and Gill Diamond

PNAS | October 23, 2007 | vol. 104 | no. 43 | 16793-16797

Copper-free click chemistry for dynamic in vivo imaging

Jeremy M. Baskin*, Jennifer A. Prescher*, Scott T. Laughlin*, Nicholas J. Agard*, Pamela V. Chang*, Isaac A. Miller*, Anderson Lo*, Julian A. Codelli*, and Carolyn R. Bertozzi

Dynamic imaging of proteins in live cells is routinely performed by using genetically encoded reporters, an approach that cannot be extended to other classes of biomolecules such as glycans and lipids. Here, we report a Cu-free variant of click chemistry that can label these biomolecules rapidly and selectively in living systems, overcoming the intrinsic toxicity of the canonical Cu-catalyzed reaction. The critical reagent, a substituted cyclooctyne, possesses ring strain and electron-withdrawing fluorine substituents that together promote the [3 + 2] dipolar cycloaddition with azides installed metabolically into biomolecules. This Cu-free click reaction possesses comparable kinetics to the Cu-catalyzed reaction and proceeds within minutes on live cells with no apparent toxicity. With this technique, we studied the dynamics of glycan trafficking and identified a population of sialoglycoconjugates with unexpectedly rapid internalization kinetics.

Accounts of Chemical Research 2007, 40 (10), 1057–1065

A Journey in Structure-Based Drug Discovery: From Designed Peptides to Protein Surface Topomimetics as Antibiotic and Antiangiogenic Agents

Ruud P. M. Dings and Kevin H. Mayo

Most biological events are mediated through molecular interactions by proteins, and because proteins are composed of structural units like helices, β-sheets and turns, small peptides and peptidomimetics may be used to mimic their biological effects and even as therapeutic agents in the clinic. Here, we present a structure-based, scaffold-driven approach to design bioactive peptides and peptidomimetics. Initially, we designed a novel series of β-sheet-forming peptides that mimic the activities of both antibiotic bacterial membrane disrupting peptides and antiangiogenic proteins. We subsequently used structure–activity relationships to reduce the design to partial peptide mimetics and then to fully nonpeptide topomimetics. Some of these agents are currently in extensive preclinical studies for further development as drug candidates against infectious disease and cancer.

New Journal of Chemistry, 2007, 31, 1899 - 1906

Synthesis and characterisation of O-6-alkylthio- and perfluoroalkylpropanethio--cyclodextrins and their O-2-, O-3-methylated analogues

Bernard Bertino Ghera, Florent Perret, Anne Baudouin, Anthony W. Coleman and Hélène Parrot-Lopez

The synthesis of twelve alkylthio- or perfluoroalkylpropanethio--cyclodextrin derivatives and their O-2-, O-3-methylated analogues are described. The coupling reaction involves firstly the basic in situ hydrolysis of alkylperfluoropropane isothiouronium iodide or alkylisothiouronium bromide, then reaction with an -cyclodextrin modified at the C-6 position by an iodine or methylsulfonyl group. The interfacial properties of these new compounds have been determined by the studies of their mono-molecular layer at the air–water interface.

Graphical abstract image for this article  (ID: b703894a)

New Journal of Chemistry, 2007, 31, 1853 - 1873


Carbo-mers: from skeleton to function

Valérie Maraval and Remi Chauvin

Since it has been proposed in 1995, the carbo-mer definition has been mainly applied to saturated and unsaturated rings of molecular skeletons, in view of studying their (homo)-aromatic character as compared to the electronic (de)localisation prevailing in the parent molecules. More generally, even acyclic or partial ethynylogues of common molecules exert fascination because the rigid expansion (preserving local symmetry) brought by the inserted acetylenic units gave them the status of "first-level nano-objects" When the C2 insertion applies to the first shell of bonds at a given carbon or hetero-atom, the "exploded"unit can be considered a local carbo-mer of the corresponding function. The chemistry of molecules featuring a per-alkynylated atom is herein surveyed and perspectives are proposed. Some of them are "mysteriously" stable, while other remain "surprisingly" unknown in spite of their structural simplicity.

Graphical abstract image for this article  (ID: b710727g)

Friday, November 2, 2007

Biomaterials, Volume 28, Issue 34, pp.5007-5204 (December 2007)

Reconstruction of functional tissues with cell sheet engineering
Pages 5033-5043
Joseph Yang, Masayuki Yamato, Tatsuya Shimizu, Hidekazu Sekine, Kazuo Ohashi, Masato Kanzaki, Takeshi Ohki, Kohji Nishida and Teruo Okano

Smart biomaterials design for tissue engineering and regenerative medicine
Pages 5068-5073
Mark E. Furth, Anthony Atala and Mark E. Van Dyke

Microengineered hydrogels for tissue engineering
Pages 5087-5092
Ali Khademhosseini and Robert Langer

A multi-functional scaffold for tissue regeneration: The need to engineer a tissue analogue
Pages 5093-5099
Filippo Causa, Paolo A. Netti and Luigi Ambrosio

Hydrogel biomaterials: A smart future?

Pages 5185-5192
Jindřich Kopeček

Biomacromolecules, Volume 8, Issue 10, Oct 2007

Hemocompatibility of Hydrophilic Antimicrobial Copolymers of Alkylated 4-Vinylpyridine
Bradley C. Allison, Bruce M. Applegate, and Jeffrey P. Youngbloodpp
pp 2995 - 2999

Fabrication of Multiresponsive Shell Cross-Linked Micelles Possessing pH-Controllable Core Swellability and Thermo-Tunable Corona Permeability
Xiaoze Jiang, Zhishen Ge, Jian Xu, Hao Liu, and Shiyong Liupp
pp 3184 - 3192

Thursday, November 1, 2007

Progress in Polymer Science, Volume 32, Issue 10-11, Pages 1135-1392 (November 2007)

Spherical polyelectrolyte brushes
Pages 1135-1151
M. Ballauff

Directing the self-assembly of block copolymers
Pages 1152-1204
S.B. Darling
Smart polymers: Physical forms and bioengineering applications

Pages 1205-1237
Ashok Kumar, Akshay Srivastava, Igor Yu Galaev and Bo Mattiasson

Thermosensitive water-soluble copolymers with doubly responsive reversibly interacting entities
Pages 1275-1343
Ivaylo Dimitrov, Barbara Trzebicka, Axel H.E. Müller, Andrzej Dworak and Christo B. Tsvetanov