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Tuesday, April 8, 2008
Biomaterials Volume 29, Issue 16, Pages 2433-2564 (June 2008)
Abby W. Morgan, Kristen E. Roskov, Sheng Lin-Gibson, David L. Kaplan, Matthew L. Becker , and Carl G. Simon Jr.
The effect of blending two silk proteins, regenerated Bombyx mori fibroin and synthetic spidroin containing RGD, on silk film material structure (β-sheet content) and properties (solubility), as well as on biological response (osteoblast adhesion, proliferation and differentiation) was investigated. Although the elasticity and strength of silks make them attractive candidates for bone, ligament, and cartilage tissue engineering applications, silk proteins generally lack bioactive peptides for enhancing cell functions. Thus, a synthetic spider silk, spidroin, containing two RGD cell adhesive sequences (RGD-spidroin) was engineered. RGD-spidroin was blended with different ratios of fibroin and spun coat into films on glass coverslips. β-Sheet formation, contact angle, surface topography and RGD surface presentation were characterized and correlated with cell behavior. We found that the amount of β-sheet formation was directly related to the RGD-spidroin content of the blends after annealing, with the pure RGD-spidroin demonstrating the highest amount of β-sheet content. The increased β-sheet content improved film stability under culture conditions. A new visualization technique demonstrated that the RGD presentation on the film surface was affected by both the RGD-spidroin content and annealing conditions. It was determined that 10 mass% RGD-spidroin was necessary to improve film stability and to achieve osteoblast attachment and differentiation.
Angewandte Chemie Int. Ed. 17/08-12/08
Abhijit Mishra, Vernita D. Gordon, Lihua Yang, Robert Coridan, Gerard C. L. Wong
Anti-MRSA Agent Discovery Using Diversity-Oriented Synthesis (p 2808-2812)
Gemma L. Thomas, Richard J. Spandl, Freija G. Glansdorp, Martin Welch, Andreas Bender, Joshua Cockfield, Jodi A. Lindsay, Clare Bryant, Derek F. J. Brown, Olivier Loiseleur, Hélène Rudyk, Mark Ladlow, David R. Spring
Sequence-Based Design of
W. Seth Horne, Melissa D. Boersma, Matthew A. Windsor, Samuel H. Gellman
Coordination Copolymerization of Polar Vinyl Monomers H2C
Andreas Berkefeld, Stefan Mecking
Alternating Copolymerizations Using a Grubbs-Type Initiator with an Unsymmetrical, Chiral N-Heterocyclic Carbene Ligand (p 2615-2618)
Kati Vehlow, Dongren Wang, Michael R. Buchmeiser, Siegfried Blechert
Single Crystals with Complex Form via Amorphous Precursors (p 2351-2353)
Helmut Cölfen
A Virus-Mimetic Nanogel Vehicle (p 2418-2421)
Eun Seong Lee, Dongin Kim, Yu Seok Youn, Kyung Taek Oh, You Han Bae
A Polymeric Molecular
Francesco Valle, Giampaolo Zuccheri, Anna Bergia, Lee Ayres, Alan E. Rowan, Roeland J. M. Nolte, Bruno Samorì
Biomacromolecules, Vol 9, Iss 3 (March 08)
Yusuke Goto, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, and Kazuhiko Ishihara
pp 828 - 833
Journal of Polymer Science Part A: Polymer Chemistry, Vol 48, Iss 7 - 8 (April 08)
Muris Kobalija, Andrew R. Bogdan, Sarah L. Poe, Fernando Escobedo, D. Tyler Mcquade
Iss 7 - (p 2309-2315)
Self-assembled organic nanotubes: Toward attoliter chemistry
Toshimi Shimizu
Iss 8 - (p 2601-2611)
Monday, April 7, 2008
Adv. Mater. 2008, 20, 1099–1104
Khoa Nguyen, Miguel Monteverde, Arianna Filoramo,* Laurence Goux-Capes,
Sebastien Lyonnais, Pascale Jegou, Pascal Viel, Marcelo Goffman, and Jean-Philippe
Bourgoin
Macromolecules 2008, 41, 1929-1936
Polymerizable N,N-Dialkylmethacrylamide
Takashi Suzuki, Jun-ichi Kusakabe, and Takashi Ishizone*
Macromolecules 2008, 41, 1909-1911
Frederik Wurm, Jorg Nieberle, and Holger Frey
Sunday, April 6, 2008
ACS Chem. Biol., vol 3, iss 3, (March 20, 2008)
Nice plot of fluorophore brightness vs. wavelength of maximum absorption for the major classes of fluorophores.

Chem. Rev., vol 108, no 2 (February 2008)
Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species
Ji
pp 462 - 493
Section on SPR to study nonfouling surfaces
The whole issue is on Modern Topics in Chemical Sensing
JACS, vol 130, no 12 (March 26, 2008)
Imparting Nanoparticle Function with Size-Controlled Amphiphilic Polymers
Yingchuan Chen, Rahul Thakar, and Preston T. Snee
pp 3744 - 3745
JACS, vol 130, no 11 (March 19, 2008)
Hierarchical Interfacial Assembly of ABC Triblock Copolymer
Jiwen Hu, Guojun Liu, and Gabriel Nijkang
pp 3236 - 3237

Breathing Life into Polycations: Functionalization with pH-Responsive Endosomolytic Peptides and Polyethylene Glycol Enables siRNA Delivery
Martin Meyer, Alexander Philipp, Reza Oskuee, Claudia Schmidt, and Ernst Wagner
pp 3272 - 3273
JACS, vol 130, no 10 (March 12, 2008)
Cellular Uptake of a Fluorescent Calix[4]arene Derivative
Ruth Lalor, Hugo Baillie-Johnson, Carl Redshaw, Susan E. Matthews, and Anja Mueller
pp 2892 - 2893

Minimally Cationic Cell-Permeable Miniature Proteins via
Betsy A. Smith, Douglas S. Daniels, Abigail E. Coplin, Gregory E. Jordan, Lynn M. McGregor, and Alanna Schepartz
pp 2948 - 2949

Neuroactive Chondroitin Sulfate Glycomimetics
Manish Rawat, Cristal I. Gama, John B. Matson, and Linda C. Hsieh-Wilson
pp 2959 - 2961
Wednesday, April 2, 2008
Macromol Rapid Commun 06/2008 & 07/2008
Thomas Junkers, Edgar H. H. Wong, Zachary Szablan, Thomas P. Davis,
Martina H. Stenzel, Christopher Barner-Kowollik*
Red Ionic Water-Soluble Imidazolium-Containing Polydiacetylene
Kamel Chougrani, Jérome Deschamps, Sylvain Dutremez, Arie van der Lee, Thierry Barisien, Laurent Legrand, Michel Schott, Jean-Sébastien Filhol, Bruno Boury*
A Novel Approach to Prepare Porous Poly(N-isopropylacrylamide) Hydrogel with Superfast Shrinking Kinetics
Jian-Tao Zhang, Klaus D. Jandt*
Friday, March 28, 2008
Science, VOL 319, ISSUE 5871, PAGES 1715-1882, 28 MARCH 2008
SCIENCE AND COMMERCE: Science by the Masses
J. Travis
pg. 1750-1752
Books
SCIENCE AND THE ARTS: Another Approach to Consilience
J. Labinger
pg. 1763.
Perspectives
MATERIALS SCIENCE: Multitasking in Tissues and Materials
P. B. Messersmith
pg. 1767-1768.
Reports
Self-Assembly of Large and Small Molecules into Hierarchically Ordered Sacs and Membranes
R. M. Capito, H. S. Azevedo, Y. S. Velichko, A. Mata, and S. I. Stupp
pg. 1812-1816.
The Transition from Stiff to Compliant Materials in Squid Beaks
A. Miserez, T. Schneberk, C. Sun, F. W. Zok, and J. H. Waite
pg. 1816-1819.
Thursday, March 27, 2008
organic letters, 2008, 10, 1481
Mei Zhu, Mingjian Yuan, Xiaofeng Liu, Jialiang Xu, Jing Lv, Changshui Huang,
Huibiao Liu, Yuliang Li,* Shu Wang, and Daoben Zhu
Organic Letters, 2008, 10, 1469
Thomas Rehm,† Vladimir Stepanenko,† Xin Zhang,† Frank Wu1rthner,†
Franziska Gro1hn,‡ Katja Klein,‡ and Carsten Schmuck*,†


Monday, March 24, 2008
Organic Letters, 2008, 10, 1275
Hai-Yu Hu,†,‡ Jun-Feng Xiang,† Yong Yang,† and Chuan-Feng Chen*,†
Thursday, March 20, 2008
Nano Letters, Vol. 8, Iss. 2, February 2008.
Pascale R. Leroueil, Stephanie A. Berry, Kristen Duthie, Gang Han, Vincent M. Rotello, Daniel Q. McNerny, James R. Baker, Jr., Bradford G. Orr, and Mark M. Banaszak Holl, pp 420 - 424.
Nature, Vol. 451, Number 7184.
Yu He, Tao Ye, Min Su, Chuan Zhang, Alexander E. Ribbe, Wen Jiang & Chengde Mao, p198.
Nature, Vol. 452, Number 7183.
Multi-membrane hydrogels
Sébastien Ladet, Laurent David & Alain Domard, p76.
Nature, Vol. 451, Number 7181.
Self-healing and thermoreversible rubber from supramolecular assembly
Philippe Cordier, François Tournilhac, Corinne Soulié-Ziakovic & Ludwik Leibler, p977.
Nature, Vol. 451, Number 7179.
P605.
Building better batteries
M. Armand & J.-M. Tarascon, p652.
An updatable holographic three-dimensional display
Sava Tay, P.-A. Blanche, R. Voorakaranam, A. V. Tunç, W. Lin, S. Rokutanda, T. Gu, D. Flores, P. Wang, G. Li, P. St Hilaire, J. Thomas, R. A. Norwood, M. Yamamoto & N. Peyghambarian, p694.
Wednesday, March 19, 2008
Science, VOL 319, ISSUE 5869, PAGES 1453-1551
SCIENCE CAREERS: Playing Well With Industry
E. Pain
pg. 1548-1551.
SCIENCE CAREERS: Business Financing for Your Research
A. Kotok
pg. 1549.
SCIENCE CAREERS: Finding Industry Funding
S. Carpenter
pg. 1550-1551.
News of the Week:
BIOMEDICAL RESEARCH: $300 Million in Private Money for New Investigators
J. Kaiser
pg. 1469.
SCIENTIFIC WORKPLACE: Indian Government Offers Helping Hand to Women Scientists
P. Bagla
pg. 1470b.
News Focus:
GRADUATE TRAINING: NSF Fellowships Called Powerful Tool for Building the Pipeline
J. Mervis
pg. 1477.
Perspectives
MATERIALS SCIENCE: The New Diamond Age?
P. W. May
pg. 1490-1491.
Reports
Synthesis of Macrocyclic Copolymer Brushes and Their Self-Assembly into Supramolecular Tubes
M. Schappacher, and A. Deffieux
pg. 1512-1515.
Tuesday, March 11, 2008
Nature Reviews Microbiology, Vol 6, No. 3 (March 2008)
Membrane lipid homeostasis in bacteria
Yong-Mei Zhang & Charles O. Rock
pp. 222-234Antimicrobial Agents and Chemotherapy, Vol 52, Iss. 3, (March 2008)
Dat Tran, Patti Tran, Kevin Roberts, George Ösapay, Justin Schaal, Andre Ouellette, and Michael E. Selsted
pp. 944-953
Thomas R. Fritsche, Paul R. Rhomberg, Helio S. Sader, and Ronald N. Jones
pp. 1187-1189
Biomacromolecules, Vol 9, Iss 3 (March 2008)
Stefano Tugulu and Harm-Anton Klok
pp 906 - 912
Monday, March 10, 2008
Biomaterials, Volume 29, Issue 14, May 2008
Jinah Kim, Anthony Conway and Anuj Chauha
Abstract
We developed extended wear silicone hydrogel soft contact lenses that deliver ophthalmic drugs for an extended period of time ranging from weeks to months. Silicone hydrogels comprising of N,N-dimethylacrylamide, 3-methacryloxypropyltris(trimethylsiloxy)silane, bis-alpha,omega-(methacryloxypropyl) polydimethylsiloxane, 1-vinyl-2-pyrrolidone, and ethylene glycol dimethacrylate were prepared with varying ratios of monomers and transport of three different ophthalmic drugs, timolol, dexamethasone, and dexamethasone 21-acetate was explored. All the silicone hydrogels of 0.1 mm thickness exhibit diffusion limited transport and extended release varying 20 days up to more than three months depending on the compositions of hydrophobic and hydrophilic components of silicone hydrogels. Also, there are multiple time scales in transport of at least certain molecules, which is perhaps due to the complex microstructure of these gels. The mechanical and physical properties of lenses such as ion permeability, equilibrium water content, transparency, and surface contact angles of some of the gels are suitable for contact lens application.
Biomaterials, Volume 29, Issue 14, May 2008, Pages 2164-2172
Biomaterials
Pages 2153-2163
Lihui Weng, Andrew Gouldstone, Yuhong Wu and Weiliam Chen
Fig. 1. Illustration of the living radical feature of CLiPP system. (A) The CLiPP photopolymer system forms a crosslinked polymer network upon exposure to UV light, incorporating DTC groups as polymer chain end-caps. DTC groups remain on the polymer surface. (B) Upon subsequent exposure to UV light, DTC and carbon radicals are reformed. (C) Carbon radicals can propagate through other vinyl groups. (D) The DTC radicals then re-cap the new carbon radical. Steps (A) through (D) continue until UV light is terminated or all of the materials are consumed. This process enables facile modification of polymer surfaces with brush grafted functional materials (E), or with crosslinkable materials (F).
Vol. 41, No. 2 February 2008 315-326 ACCOUNTS OF CHEMICAL RESEARCH
ZHIMOU YANG, GAOLIN LIANG, AND BING XU
In this Account, we discuss the use of enzymes to trigger and control the self-assembly of small molecules for hydrogelation,which takes place in vitro or in vivo, extra- or intracellularly. Using phosphatase, thermolysin, -lactamase, and phosphatase/kinase as examples, we illustrate the design and application of enzyme-catalyzed or -regulated formation of supramolecular hydrogels that offer a new strategy for detecting the activity of enzymes, screening for enzyme inhibitors,
typing bacteria, drug delivery systems, and controlling the fate of cells. Since the expression and distribution of enzymes differ by the types and states of cells, tissues, and organs, using an enzymatic reaction to convert precursors into hydrogelators that self-assemble into nanofibers as the matrices of the hydrogel, one can control the delivery, function, and response of a hydrogel according to a specific biological condition or environment, thus providing an accessible route to create sophisticated materials for biomedicine. Particularly, intracellular enzymatic hydrogelation of small molecules offers a unique means for scientists to integrate molecular self-assembly with inherent enzymatic reactions inside cells for developing new biomaterials and therapeutics at the supramolecular level and improving the basic understanding of dynamic molecular selfassembly in water.
PNAS | February 19, 2008 | vol. 105 | no. 7 | 2307-2312
PNAS | February 19, 2008 | vol. 105 | no. 7 | 2586-2591
Frank Gu, Liangfang Zhang, Benjamin A. Teply, Nina Mann, Andrew Wang,, Aleksandar F. Radovic-Moreno, Robert Langer, and Omid C. Farokhzad
Science, VOL 319, ISSUE 5867-8, PAGES 1157, 1414 Feb-Mar 2008
PEER REVIEW: NIH Urged to Focus on New Ideas, New Applicants
J. Kaiser (29 February 2008)
Science 319 (5867), 1169.
SCIENTIFIC MISCONDUCT: Chemist Found Responsible for Ethical Breaches
R. F. Service (29 February 2008)
Science 319 (5867), 1170b-1171b.
RESEARCH FUNDING: Philip Morris Pulls the Plug on Controversial Research Program
D. Grimm (29 February 2008)
Science 319 (5867), 1173a.
Perspectives
MATERIALS SCIENCE: New Materials at a GlanceM. J. Brett, and M. M. Hawkeye (29 February 2008)
Science 319 (5867), 1192-1193
Reports
Stimuli-Responsive Polymer Nanocomposites Inspired by the Sea Cucumber Dermis
J. R. Capadona, K. Shanmuganathan, D. J. Tyler, S. J. Rowan, and C. Weder (7 March 2008)
Science 319 (5868), 1370-1374.
Sunday, March 9, 2008
Chemical Society Reviews

Catalytic methods for the destruction of chemical warfare agents under ambient conditions
Bryan M. Smith
Chem. Soc. Rev., 2008, 37, 470 - 478,
Chemistry - A European Journal

Self-Assembled Structures in Organogels of Amphiphilic Diblock Codendrimers
Miao Yang, Zijian Zhang, Fei Yuan, Wei Wang, Sandra Hess, Karen Lienkamp, Ingo Lieberwirth, Gerhard Wegner
Friday, March 7, 2008
JACS vol 130, no 9 (Mar 5, 2008)
Stoichiometric Functionalization of Gold Nanoparticles in Solution through a Free Radical Polymerization Approach
Christian Krüger, Seema Agarwal, and Andreas Greiner
pp 2710 - 2711

Sub-100 nm Patterning of Supported Bilayers by Nanoshaving Lithography
Jinjun Shi, Jixin Chen, and Paul S. Cremer
pp 2718 - 2719

A Templating Approach for Monodisperse Self-Assembled Organic Nanostructures
Steve R. Bull, Liam C. Palmer, Nathaniel J. Fry, Megan A. Greenfield, Benjamin W. Messmore, Thomas J. Meade, and Samuel I. Stupp
pp 2742 - 2743

Self-delivering Nanoemulsions for Dual Fluorine-19 MRI and Fluorescence Detection
Jelena M. Janjic, Mangala Srinivas, Deepak K.K. Kadayakkara, and Eric T. Ahrens
pp 2832 - 2841

JACS vol 130, no 8 (Feb 27, 2008)
Surface Patterning with Fluorescent Molecules Using Click Chemistry Directed by Scanning Electrochemical Microscopy
Sung-Yu Ku, Ken-Tsung Wong, and Allen J. Bard
pp 2392 - 2393
JACS vol 130 no 7 (Feb 20, 2008)
Lipid-Protein Nanoscale Bilayers: A Versatile Medium for NMR Investigations of Membrane Proteins and Membrane-Active Peptides
Ekaterina N. Lyukmanova, Zakhar O. Shenkarev, Alexander S. Paramonov, Alexander G. Sobol, Tatiana V. Ovchinnikova, Vladimir V. Chupin, Mikhail P. Kirpichnikov, Marcel J. J. Blommers, and Alexander S. Arseniev
pp 2140 - 214
Thursday, March 6, 2008
chembiochem, 2008, 9, 634
Hyeonseok Yoon,[a] June-Hyung Kim,[b] Nahum Lee,[c] Byung-Gee Kim,[c] and Jyongsik Jang*[a]
organic letters, 2008, 10, 897
Takashi Sasaki and James M. Tour*
This time, they call it Nanoworm, instead of Nanocar.
Tuesday, March 4, 2008
Angewandte Chemie International Edition 06-2008 to 12-2008
Highly Stable Giant Supramolecular Vesicles Composed of 2D Hydrogen-Bonded Sheet Structures of Guanosine Derivatives (p 1038-1041)
Isao Yoshikawa, Jun Sawayama, Koji Araki
Self-Organization of Electroactive Materials: A Head-to-Tail Donor-Acceptor Supramolecular Polymer (p 1094-1097)
Gustavo Fernández, Emilio M. Pérez, Luis Sánchez, Nazario Martín
Angewandte Chemie International Edition 7/2008
Nanofibers and Lyotropic Liquid Crystals from a Class of Self-Assembling
William C. Pomerantz, Virany M. Yuwono, Claire L. Pizzey, Jeffery D. Hartgerink, Nicholas L. Abbott, Samuel H. Gellman
Varun Sambhy, Blake R. Peterson, Ayusman Sen
Virion-Mimicking Nanocapsules from pH-Controlled Hierarchical Self-Assembly for Gene Delivery (p 1260-1264)
Peisheng Xu, Shi-Yan Li, Qun Li, Edward A. Van Kirk, Jun Ren, William J. Murdoch, Zhaojie Zhang, Maciej Radosz, Youqing Shen
Vesicle Formation from Reactive Surfactants (p 1323-1325)
Helmut H. Zepik, Peter Walde, Takashi Ishikawa
Angewandte Chemie International Edition 8/2008
Tris(2,2
Monika C. Haberecht, Jan M. Schnorr, Ekaterina V. Andreitchenko, Christopher G. Clark Jr., Manfred Wagner, Klaus Müllen
Angewandte Chemie International Edition 10/2008
Polymer Vesicles Containing Small Vesicles within Interior Aqueous Compartments and pH-Responsive Transmembrane Channels (p 1875-1878)
Hsin-Cheng Chiu, Yue-Wen Lin, Yi-Fong Huang, Chih-Kai Chuang, Chorng-Shyan Chern
Angewandte Chemie International Edition 11/2008
Aurelie Brizard, Marc Stuart, Kjeld van Bommel, Arianna Friggeri, Menno de Jong, Jan van Esch
Hierarchically Structured Microparticles Formed by Interfacial Instabilities of Emulsion Droplets Containing Amphiphilic Block Copolymers (p 2113-2116)
Jintao Zhu, Ryan C. Hayward
Angewandte Chemie International Edition 12/2008
pH-Responsive Supramolecular Nanovalves Based on Cucurbit[6]uril Pseudorotaxanes (p 2222-2226)
Sarah Angelos, Ying-Wei Yang, Kaushik Patel, J. Fraser Stoddart, Jeffrey I. Zink
Reversible Switching between Macrocyclic and Polymeric States by Morphological Control in a Constitutional Dynamic System (p 2240-2243)
Sébastien Ulrich, Jean-Marie Lehn
Macromol. Rapid Commun 5/2008
Control of the Dynamic Motion of a Gel Actuator Driven by the Belousov-Zhabotinsky Reaction (p 401-405)
Shingo Maeda, Yusuke Hara, Ryo Yoshida, Shuji Hashimoto
Peculiar
Jiro Kumaki, Takehiro Kawauchi, Eiji Yashima
Macromol. Rapid Commun. 4/2008
Issue Edited by M. Antonietti, A. D. Schlüter
...have a look at this! Both editors are well-known in Germany, and most of the corresponding authors are young European polymer people who just started their own groups.Macromol. Rapid Commun. 3/2008
Ricardo Losada, Christine Wandrey
...the paper isn't particularly exciting, however the monomer is nice and commercially available!
Self-Assembly of Diblock Copolymers into Novel Snowflake-Shaped Aggregates Driven by Quadruple Hydrogen Bonding (p 258-263)
Yu Wang, Yu Cao, Yipeng Qiu, Liming Tang
Nice TEM images.
Journal of Polymer Science Part A: Polymer Chemistry, Vol.46 Iss. 6 (March 2008)
Ho-Joong Kim, Yong-Beom Lim, Myongsoo Lee
(p 1925-1935)
Solvent influence on the orthogonality of noncovalently functionalized terpolymers
Caroline Burd, Marcus Weck
(p 1936-1944)
Monday, March 3, 2008
Adv. Mater. 2008, 20, 867–877
Benefit Biomedical Technologies
David W. Grainger and David G. Castner
Macromolecules 2008, 41, 1175-1183
Polynorbornenes Carrying 2,2,6,6-Tetramethylpiperidine-1-oxy
Radicals at High Density
Toru Katsumata, Jinqing Qu, Masashi Shiotsuki, Masaharu Satoh, Jun Wada,
Jun Igarashi, Kenji Mizoguchi, and Toshio Masuda
Sunday, March 2, 2008
Biochemistry 2008, 47

Biochemistry 2008, 47, 3051–3060
Small Changes in the Primary Structure of Transportan 10 Alter the Thermodynamics and Kinetics of its Interaction with Phospholipid Vesicles
Lindsay E. Yandek, Antje Pokorny, and Paulo F. F. Almeida

Biochemistry 2008, 47, 2841–2849
Melittin Interaction with Sulfated Cell Surface Sugars
Gabriela Klocek and Joachim Seelig
