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Monday, December 15, 2008
Chem. Eur. J. 2008, 14, 10949 – 10957
Functionalization of Linear Polymer Chains
Sebastian Pfeifer and Jean-FranÅois Lutz
Chem. Eur. J. 2008,
Design of Antibacterial Copolymers
Gregory J. Gabriel,[a] Janet A. Maegerlein,[a] Christopher F. Nelson,[b]
Jeffrey M. Dabkowski,[b] Tarik Eren,[a] Klaus Nsslein,[b] and Gregory N. Tew*
Acc. Chem. Res. Vol. 41, Iss. 11
Large review on Cross Coupling reactions: reagents, catalysts, Suzuki, Sonogashira, etc.
Nanoletters, Vol. 8, No. 12
D. S. Deng, N. D. Orf, A. F. Abouraddy, A. M. Stolyarov, J. D. Joannopoulos, H. A. Stone and Y. Fink, pp 4265–4269
J. Mater. Chem., 2009, 19, 60 - 62
Munenori Yamada, Mizuho Kondo, Ryo Miyasato, Yumiko Naka, Jun-ichi Mamiya, Motoi Kinoshita, Atsushi Shishido, Yanlei Yu, Christopher J. Barrettc and Tomiki Ikeda
ACS Nano
Surface Morphology Diagram for Cylinder-Forming Block Copolymer Thin Films
Xiaohua Zhang†, Brian C. Berry†, Kevin G. Yager†, Sangcheol Kim†, Ronald L. Jones†, Sushil Satija‡, Deanna L. Pickel§, Jack F. Douglas†* and Alamgir Karim†*
ACS Nano
Abstract
In this study, we describe optical detection of antibody-conjugated nanoparticles bound to surgically resected human pancreatic cancer tissue. Gold nanoparticles stabilized by heterobifunctional polyethylene glycol (PEG) were prepared using ∼15 nm spherical gold cores and covalently coupled to F19 monoclonal antibodies. The heterobifunctional PEG ligands contain a dithiol group for stable anchoring onto the gold surface and a terminal carboxy group for coupling of antibodies to the outside of the PEG shell. The nanoparticle−antibody bioconjugates form highly stable dispersions and exhibit long-term resistance to agglomeration. This has been demonstrated by dynamic light scattering, size exclusion chromatography, and transmission electron microscopy. The nanoparticle bioconjugates were used to label tumor stroma in approximately 5 μm thick sections of resected human pancreatic adenocarcinoma. After rinsing away nonbound nanoparticles and fixation, the tissue samples were imaged by darkfield microscopy near the nanoparticle resonance scattering maximum (∼560 nm). The images display pronounced tissue features and suggest that this novel labeling method could provide for facile identification of cancer tissue. Tumor samples treated with gold nanoparticles conjugated to nonspecific control antibodies and noncancerous pancreatic tissue treated with mAb-F19-conjugated gold nanoparticles both exhibited correctly negative results and showed no tissue staining.
Biochimica et Biophysica Acta 1778 (2008) 2749–2756
Binding, uptake and endocytotic pathway
L. Di Marzio, C. Marianecci , B. Cinque , M. Nazzarri , A.M. Cimini, L. Cristiano, M.G. Cifone,
F. Alhaique, M. Carafa
Organic & Biomolecular Chemistry, 2009, 7
coil peptides direct colloid assembly†
Sara C. Wagner, Meike Roskamp, Helmut Colfen, Christoph Bottcher, Sabine Schlecht* and Beate Koksch*
Very long-chain fatty tails for enhanced transfection†
Aleksandra Liberska, Asier Unciti-Broceta and Mark Bradley*
ACS Chem. Bio.
Artem Cherkasov, Kai Hilpert, Håvard Jenssen, Christopher D. Fjell, Matt Waldbrook, Sarah C. Mullaly, Rudolf Volkmer, and Robert E.W. Hancock
Monday, December 8, 2008
New journal chemistry, 2008, 32, 1850
Caroline J. Scheuermann ne´ e Taylor*a and Benjamin D. Wardb
mini review of Cobalt chemistry
Tuesday, November 11, 2008
Small, 2008, 4, 1711-1715
Advanced materials, 2008, 20: 1-5
Biochimica et Biophysica Acta 1778 (2008) 2487–2495
chimeras: lessons for the design of new cell-penetrating peptides
Camilla Foged, Henrik Franzyk, Shervin Bahrami, Sven Frokjaer, Jerzy W. Jaroszewski,
Hanne M. Nielsen, Christian A. Olsen
Biochemistry 2008, 47, 11070–11076
Julie M. Glasscock,‡ Yongjin Zhu,§ Pramit Chowdhury,§ Jia Tang,§ and Feng Gai*
Monday, November 10, 2008
JACS, Vol. 130, No. 45
Rolf Chelmowski,† Stephan David Koster,‡ Andreas Kerstan,† Andreas Prekelt,† Christian Grunwald,§ Tobias Winkler,| Nils Metzler-Nolte,‡ Andreas Terfort,| and Christof Wo¨ ll*,†
Design of Polymeric Carriers for Cancer-Specific Gene Targeting: Utilization of Abnormal Protein Kinase Cr Activation in Cancer Cells
Jeong-Hun Kang, Daisuke Asai,§ Jong-Hwan Kim, Takeshi Mori, Riki Toita,
Tetsuro Tomiyama, Yoji Asami, Jun Oishi, Yuko T. Sato,Takuro Niidome,Byungdug Jun, Hideki Nakashima, and Yoshiki Katayama
Encapsulation Efficiency Measured on Single Small Unilamellar Vesicles
Brian Lohse, Pierre-Yves Bolinger, and Dimitrios Stamou
Anionic Amphiphilic Dendrimers as Antibacterial Agents
Steven R. Meyers, Frank S. Juhn, Aaron P. Griset, Nathanael R. Luman, and Mark W. Grinstaff*
Nernstian Adsorbate-like Bulk Layer of Organic Radical Polymers for High-Density Charge Storage Purposes
Kenichi Oyaizu, Yuko Ando, Hiroaki Konishi, and Hiroyuki Nishide
Langmuir, Vol 24, Iss 21, Nov 2008
Min Kyoon Shin, Sun I. Kim, Seon Jeong Kim, Sang Yoon Park, Young Hoon Hyun, YoungPak Lee, Kyung Eun Lee, Sung-Sik Han, Dong-Pyo Jang, Young-Bo Kim, Zang-Hee Cho, Insuk So, and Geoffrey M. Spinks
pp 12107 - 12111
Antifouling Properties of Poly(methyl methacrylate) Films Grafted with Poly(ethylene glycol) Monoacrylate Immersed in Seawater
O. Iguerb, C. Poleunis, F. Mazéas, C. Compère, and P. Bertrand
pp 12272 - 12281
How To Prevent the Loss of Surface Functionality Derived from Aminosilanes
Emily Asenath Smith and Wei Chen
pp 12405 - 12409
Diffusion of Macromolecules on Lipid Vesicles
W. T. Góźdź
pp 12458 - 12468
Langmuir, Vol 24, Iss 20, Oct 2008
Kingo Takiguchi, Ayako Yamada, Makiko Negishi, Yohko Tanaka-Takiguchi, and Kenichi Yoshikawa
pp 11323 - 11326
Particle Size Determination Using TEM: A Discussion of Image Acquisition and Analysis for the Novice Microscopist
William D. Pyrz and Douglas J. Buttrey
pp 11350 - 11360
Enhancing Amine Terminals in an Amine-Deprived Collagen Matrix
William H. C. Tiong, Gopinath Damodaran, Hemantkumar Naik, John L. Kelly, and Abhay Pandit
pp 11752 - 11761
Transmembrane Delivery of the Cell-Penetrating Peptide Conjugated Semiconductor Quantum Dots
Bo Chen, Qiaoling Liu, Yuliang Zhang, Li Xu, and Xiaohong Fang
pp 11866 - 11871
Friday, October 17, 2008
Soft Matter, 2008, 4, 1995-1007
Advanced materials, 2008, 20: 1-17
Tuesday, October 14, 2008
Biochimica et Biophysica Acta 1778 (2008) 2026–2031
Tatiana B. Stoilova, Sergey I. Kovalchuk, Natalya S. Egorova, Andrey Y. Surovoy, Vadim T. Ivanov
New Journal Chemistry, 2008, 32,1509
Marta Kopaczyn´ ska,a Jurgen H. Fuhrhop,a Anna M. Trzeciak,*b
Jo´ zef J. Zio´ $kowskib and Robert Choukrounc
Monday, October 13, 2008
Nature, Vol. 455, Number 7209.
p85
Jarrod A. Hanson, Connie B. Chang, Sara M. Graves, Zhibo Li, Thomas G. Mason & Timothy J. Deming
Nature, Vol. 453, through Number 7212.
p446
Barack Obama accepted Nature's invitation to answer 18 science-related questions in writing; John McCain's campaign declined. Obama's answers to many of the questions are printed here; answers to additional questions (on topics including biosecurity, the nuclear weapons laboratories and US participation in international projects) can be found at http://www.nature.com/uselection. Wherever possible, Nature has noted what McCain has said at other times on these topics.
Alexandra Witze
Nanoletters, Vol. 8. Issue 10.
Electrospinning of Three-Dimensional Nanofibrous Tubes with Controllable Architectures
Daming Zhang and Jiang Chang. pp 3283 - 3287.
Bioeliminable Nanohydrogels for Drug Delivery
De Gao, Hao Xu, Martin A. Philbert, and Raoul Kopelman. pp 3320 - 3324.
J. AM. CHEM. SOC.
Sreenivasa Reddy Puniredd, Ossama Assad, and Hossam Haick*
Fragmentation of Fiberlike Structures: Sonication Studies of Cylindrical Block Copolymer Micelles and Behavioral Comparisons to Biological Fibrils
Gerald Guerin,† Hai Wang,† Ian Manners,*,‡ and Mitchell A. Winnik*,†
Cubic versus Spherical Magnetic Nanoparticles: The Role of Surface Anisotropy
G. Salazar-Alvarez, J. Qin,‡ V. Sepelak, I. Bergmann, M. Vasilakaki, K. N. Trohidou, J. D. Ardisson, W. A. A. Macedo, M. Mikhaylova, M. Muhammed, M. D. Baro , and J. Nogue´s
Organic & Biomolecular Chemistry
A newly designed anthracene derivative having gluconamides at its peripheral branches formed a photo-responsive hydrogel. SEM observation of the xerogel showed a network structure consisting of fibrils. Upon photoirradiation ( >300 nm) of the hydrogel, regioselective photodimerization of the anthracene moiety occurred to give head-to-tail photodimers and the physical state changed from the gel to the sol.
Design and synthesis of intrinsically cell-penetrating nucleopeptides†
Nucleopeptides, which are constituted of a-amino acids bearing nucleobases at their side chains, are able to penetrate into cells and to reach the nucleus without cytotoxic effects.
Langmuir, Vol 24, Iss 19, Oct 2008
Mingyu Guo, Ming Jiang, and Guangzhao Zhang
pp 10583 - 10586
Colloid-Templated Multisectional Porous Polymeric Fibers
Jung Hun Song and Ilona Kretzschmar
pp 10616 - 10620
Coupled Electrostatic, Hydrodynamic, and Mechanical Properties of Bacterial Interfaces in Aqueous Media
Fabien Gaboriaud, Michelle L. Gee, Richard Strugnell, and Jérôme F. L. Duval
pp 10988 - 10995
Langmuir, Vol 24, Iss 18, Sep 2008
Yi He, Jason Hower, Shengfu Chen, Matthew T. Bernards, Yung Chang, and Shaoyi Jiang
pp 10358 - 10364
Assembly of Organic Monolayers on Polydicyclopentadiene
Mathew Perring and Ned B. Bowden
pp 10480 - 10487
Biomacromolecules, Vol 9, Iss 10, Oct 2008
All articles are very interesting. You can take a look.
Biomacromolecules, Vol 9, Iss 9, Sep 2008
D. Matthew Eby, Karen E. Farrington, and Glenn R. Johnson
pp 2487 - 2494
Sunday, October 12, 2008
Organic letters, 2008, 10, 4283
Ningbo Zhu, Wei Hu, Shuliang Han, Qi Wang, and Dahui Zhao*
New Journal Chemistry, 2008, 32, 571
Santiago Alvarez
Do the chemical elements, Mendeleev or the Periodic Table play any role in the world of
music? Here are a few preliminary notes for an answer to that question, maybe just the
tip of an iceberg. Some suggestions are offered on music that is worth listening to,
although some of the works commented on may require more of a good sense of
humour than musical sensibility from the reader.
Friday, October 3, 2008
Journal of Polymer Science Part A: Polymer Chemistry, Vol 46, Iss 20, Oct 2008
Patrick Theato
p 6677-6687
Synthesis, characterization and cleavage of linear polymers attached to silica nanoparticles formed using thiol-acrylate conjugate addition reactions
Vaibhav S. Khire, April M. Kloxin, Charles L. Couch, Kristi S. Anseth, Christopher N. Bowman
p 6896-6906
One-pot synthesis of heterograft copolymers via graft onto by atom transfer nitroxide radical coupling chemistry
Qiang Fu, Chao Liu, Wencheng Lin, Junlian Huang
p 6770-6779
Synthesis, characterization and cleavage of linear polymers attached to silica nanoparticles formed using thiol-acrylate conjugate addition reactions
Vaibhav S. Khire, April M. Kloxin, Charles L. Couch, Kristi S. Anseth, Christopher N. Bowman
p 6896-6906
Tuesday, September 2, 2008
Accounts of Chem. Research. Vol. 41. No. 8.
Reuven Gordon, David Sinton, Karen L. Kavanagh, and Alexandre G. Brolo. pp 1049 - 1057.
Nanoletters, Vol. 8. Issue 8.
Jeong In Lee, Shin Hyo Cho, Su-Moon Park, Jin Kon Kim, Jai Kyeong Kim, Jae-Woong Yu, Young Chul Kim, and Thomas P. Russell. pp 2315 - 2320.
Nature, Vol. 453, through Number 7205.
Light-induced reactions enable three-dimensional objects to be built from simple compounds. Proteins have been added to the list of building blocks, and the resulting gels move in response to environmental cues.
April M. Kloxin & Kristi S. Anseth. p705.
Chem. Commun., 2008, 3507–3509
analysis of polymeric micro-doughnutsw
Lois Alexander,a Kevin Dhaliwal,b John Simpsonb and Mark Bradley*a
Chem. Eur. J. 2008, 00, 0 – 0
Covalently Attached to Single-Wall Carbon Nanotubes
Andreas A. Stefopoulos,[a, b] Christos L. Chochos,[a, c] Maurizio Prato,[d] George Pistolis,[e]
Kostas Papagelis,[f] Foteini Petraki,[b, g] Stella Kennou,[b, g] and Joannis K. Kallitsis*[a, b]
Chem. Eur. J. 2008, 00, 0 – 0
Phthalocyanine-Containing Complementary Organogelator Structures and In
Situ Cross-Linking by Click Chemistry
David D)az D)az,*[b] Juan Jos0 Cid,[a] Purificaci1n V3zquez,[a] and Tom3s Torres*[a]
Introduction
Bioconjugate Chem., Vol. 19, No. 8, 2008
Chelates Containing Two Water Exchange Sites
Joshua M. Bryson,† Wen-Jang Chu,§ Jing-Huei Lee,‡,§ and Theresa M. Reineke*,†
Biomaterials Volume 29, Issue 29, October 2008, Pages 3905-3913
Biochemistry 2008, 47, 9243–9250
the Physical and Biological Properties of the -Hairpin Antimicrobial Peptide
Protegrin-1
Lindsey M. Gottler,‡ Roberto de la Salud Bea,‡ Charles E. Shelburne,§ Ayyalusamy Ramamoorthy,*,‡,| and
E. Neil G. Marsh*
Biochemistry 2008, 47, 8557–8565
Phospholipid Membranes
John D. Gehman,‡ Fiona Luc,‡ Kristopher Hall,§ Tzong-Hsien Lee,§ Martin P. Boland,‡ Tara L. Pukala, John H. Bowie,| Marie-Isabel Aguilar,§ and Frances Separovic*,‡