TEW GROUP LITERATURE

Tuesday, April 28, 2009

Chem. Eur. J. 2009, 15, 3526 – 3537

A Highly Efficient Macrolactonization Method via Ethoxyvinyl Ester
Yusuke Ohba,[a] Mayuko Takatsuji,[a] Kenji Nakahara,[a] Hiromichi Fujioka,[a] and
Yasuyuki Kita

Biomaterials Volume 30, Issue 18, June 2009, Pages 3158-3166

The effect of photodynamic treatment combined with antibiotic action or host defence mechanisms on Staphylococcus aureus biofilms

Antonella Di Poto^a, Maria S. Sbarra^a, Giulio Provenza^a, Livia Visai^a^,^b and Pietro Speziale

Fig. 3. Light dose-dependent killing of staphylococcal biofilms treated with TMP. S. aureus biofilms were incubated with TMP (10 μm) in the dark and subsequently irradiated with different light doses. Surviving fractions of cells were expressed as the ratios of CFU from bacteria treated with TMP and light to CFU of bacteria treated with TMP alone. The values represented are the means of the results from duplicate biofilms. Data are representative of three replicate experiments with similar results. Error bars indicate standard errors of the means.

Biomaterials Volume 30, Issue 18, June 2009, Pages 3167-3173

An antimicrobial modified silicone peritoneal catheter with activity against both Gram positive and Gram negative bacteria

Roger Bayston^a^,^,, Leanne E. Fisher^a and Klaus Weber^b

Fig. 1. CAPD: microbial routes of entry. Bacteria can gain access to the peritoneal cavity either by contaminating the connector and the catheter lumen, or by migration from the skin exit site down the catheter track through the tissue. Two Dacron cuffs are attached to the catheter in an attempt to delay or prevent this second means.

Chem. Eur. J. 2009, 15, 4419 – 4427

A Carbon Nano-Onion–Ferrocene Donor–Acceptor System:
Synthesis, Characterization and Properties
Carla T. Cioffi,[a] Amit Palkar,[b] Frederic Melin,[b] Amar Kumbhar,[b] Luis Echegoyen,*[b]
Manuel Melle-Franco,[c] Francesco Zerbetto,*[c] G. M. Aminur Rahman,[d]
Christian Ehli,[d] Vito Sgobba,[d] Dirk M. Guldi,*[d] and Maurizio Prato

Chem. Soc. Rev., 2009, 38, 883–891

Molecular hydrogels of therapeutic agents
Fan Zhao,a Man Lung Mab and Bing Xu*

Chem. Soc. Rev., 2009, 38, 1228–1236

Polymerization reactions in porous coordination polymers
Takashi Uemura,ab Nobuhiro Yanaia and Susumu Kitagawa*ac

J. Mater. Chem., 2009, 19, 1968–1977

An improved injectable polysaccharide hydrogel: modified gellan gum
for long-term cartilage regeneration in vitro
Yihong Gong, Chunming Wang, Ruenn Chai Lai, Kai Su, Feng Zhang and Dong-an Wang*

Bioconjugate Chem. 2009, 20, 511–517

Ring-Opening Metathesis Polymerization-Based Synthesis of
ICG-Containing Amphiphilic Triblock Copolymers for in Vivo Tumor
Imaging
Koji Miki,† Yoshiaki Kuramochi,† Kazuaki Oride,† Satoru Inoue,† Hiroshi Harada,‡,§ Masahiro Hiraoka,‡,§ and
Kouichi Ohe*,†

Bioconjugate Chem. 2009, 20, 702–709

An Improved Cell-Penetrating, Caspase-Activatable, Near-Infrared
Fluorescent Peptide for Apoptosis Imaging

Dustin Maxwell,† Qing Chang,‡ Xu Zhang,‡ Edward M. Barnett,‡ and David Piwnica-Worms

Acc. Chem. Res. Vol. 42, No. 4.

From Antenna to Assay: Lessons Learned in Lanthanide Luminescence

Evan G. Moore, Amanda P. S. Samuel and Kenneth N. Raymond* pp 542–552.

Nanoletters, Vol. 9, Iss. 4.

Continuous Concentric Lamellar Block Copolymer Nanofibers with Long Range Order

Minglin Ma†§, Kirill Titievsky†, Edwin L. Thomas‡§ and Gregory C. Rutledge*†§ pp 1678–1683.

Kinetically Controlled Synthesis of Hexagonally Close- Packed Cobalt Nanorods with High Magnetic Coercivit

Yaghoub Soumare, Ce ´cile Garcia, Thomas Maurer, Gre ´gory Chaboussant,
Fre ´de ´ric Ott, Fernand Fie ´vet, Jean-Yves Piquemal,* and Guillaume Viau
Adv. Funct. Mater. 2009,19, 1–7

A Smart Nanoprobe Based On Fluorescence-Quenching PEGylated Nanogels Containing Gold Nanoparticles for Monitoring the Response to Cancer Therapy

Motoi Oishi, Atsushi Tamura, Takahito Nakamura, and Yukio Nagasaki
Adv. Funct. Mater. 2009,19, 827–834

Incorporation of Fe3O4 Nanoparticles into Organometallic Coordination Polymers by Nanoparticle Surface Modification

Sang Bok Kim, Chen Cai, Shouheng Sun, and Dwight A. Sweigart*
Angew. Chem. Int. Ed. 2009, 48, 2907 –2910

Supramolecular ABC Triblock Copolymers

Ashootosh V. Ambade, Si Kyung Yang, and Marcus Weck
Angew. Chem. Int. Ed. 2009, 48, 2894 –2898

Undulated Multicompartment Cylinders by the Controlled and Directed Stacking of Polymer Micelles with a Compartmentalized Corona

Bing Fang, Andreas Walther, Andrea Wolf, Youyong Xu, Jiayin Yuan, and Axel H. E. Mueller
Angew. Chem. Int. Ed. 2009, 48, 2877 –2880

Highly Proton-Conducting Self-Humidifying Microchannels Generated by Copolymer Brushes on a Scaffold

Basit Yameen, Anke Kaltbeitzel, Andreas Langer, Frank Mller, Ulrich Gsele,Wolfgang Knoll, Omar Azzaroni
Angew. Chem. Int. Ed. 2009, 48, 3124 –3128

Photodegradable Hydrogels for Dynamic Tuning of Physical and Chemical Properties

April M. Kloxin,¹ Andrea M. Kasko,¹^,2^* Chelsea N. Salinas,¹ Kristi S. Anseth¹^,2Science 3 April 2009:Vol. 324. no. 5923, pp. 59 - 63

A New Two-Photon-Sensitive Block Copolymer Nanocarrier

Maxime Pelletier, Martin Lepage, Jean-Franois Allard, Denis Morris,Yue Zhao
Angew. Chem. Int. Ed. 2009, 48, 3329 –3332

Molecular Recognition in Self-Assembled Integrated Circuits: Getting Smaller while under Control

Yong-beom Lim and Myongsoo Lee
Angew. Chem. Int. Ed. 2009, 48, 3394 – 3396

Monday, April 27, 2009

Nature Materials 8, 432 - 437 (2009)

A cell-free protein-producing gel

Abstract:

Proteins are important biomaterials and are generally produced in living cells. Here, we show a novel DNA hydrogel that is capable of producing functional proteins without any living cells. This protein-producing gel (termed 'the P-gel system' or 'P-gel') consists of genes as part of the gel scaffolding. This is the first time that a hydrogel has been used to produce proteins. The efficiency was about 300 times higher than current, solution-based systems. In terms of volumetric yield, the P-gel produced up to 5 mg ml^-1 of functional proteins. The mechanisms behind the high efficiency and yield include improved gene stability, higher local concentration and a faster enzyme turnover rate due to a closer proximity of genes. We have tested a total of 16 different P-gels and have successfully produced all 16 proteins including membrane and toxic proteins, demonstrating that the P-gel system can serve as a general protein production technology.

ACS Nano, 2009, 3 (3), pp 673–681

Benzaldehyde-Functionalized Polymer Vesicles

Abstract:

Polymer vesicles with diameters of ca. 100−600 nm and bearing benzaldehyde functionalities within the vesicular walls were constructed through self-assembly of an amphiphilic block copolymer PEO₄₅-b-PVBA₂₆ in water. The reactivity of the benzaldehyde functionalities was verified by cross-linking the polymersomes and also by a one-pot cross-linking and functionalization approach to further render the vesicles fluorescent, each via reductive amination. In vitro studies found these labeled nanostructures to undergo cell association

ACS Nano, 2009, 3 (3), pp 502–510

Imaging Pancreatic Cancer Using Bioconjugated InP Quantum Dots

Abstract:

n this paper, we report the successful use of non-cadmium-based quantum dots (QDs) as highly efficient and nontoxic optical probes for imaging live pancreatic cancer cells. Indium phosphide (core)−zinc sulfide (shell), or InP/ZnS, QDs with high quality and bright luminescence were prepared by a hot colloidal synthesis method in nonaqueous media. The surfaces of these QDs were then functionalized with mercaptosuccinic acid to make them highly dispersible in aqueous media. Further bioconjugation with pancreatic cancer specific monoclonal antibodies, such as anticlaudin 4 and antiprostate stem cell antigen (anti-PSCA), to the functionalized InP/ZnS QDs, allowed specific in vitro targeting of pancreatic cancer cell lines (both immortalized and low passage ones). The receptor-mediated delivery of the bioconjugates was further confirmed by the observation of poor in vitro targeting in nonpancreatic cancer based cell lines which are negative for the claudin-4-receptor. These observations suggest the immense potential of InP/ZnS QDs as non-cadmium-based safe and efficient optical imaging nanoprobes in diagnostic imaging, particularly for early detection of cancer.

Langmuir, Vol 25, Iss 8 (April 09)

Bacteria Survive Multiple Puncturings of Their Cell Walls

Zhiyong Suo†, Recep Avci*†, Muhammedin Deliorman†, Xinghong Yang‡ and David W. Pascual‡

pp 4588–4594

Sunday, April 26, 2009

Langmuir, Vol 25, Iss 5 (March 09)

Self-Assembly of Vesicles from Amphiphilic Aromatic Amide-Based Oligomers
Yun-Xiang Xu, Gui-Tao Wang, Xin Zhao*, Xi-Kui Jiang and Zhan-Ting Li*
pp 2684–2688

Separation of Coherent and Incoherent Scattering Contributions in Ellipsometric Light Scattering Experiments on Latex Mixtures
Andreas Erbe†, Klaus Tauer and Reinhard Sigel*‡
pp 2703–2710

Protein Adsorption on Poly(N-vinylpyrrolidone)-Modified Silicon Surfaces Prepared by Surface-Initiated Atom Transfer Radical Polymerization
Zhaoqiang Wu†‡§, Hong Chen*†§, Xiaoli Liu†§, Yanxia Zhang†§, Dan Li†§ and He Huang§
pp 2900–2906

Novel Zwitterionic-Polymer-Coated Silica Nanoparticles
Guangwei Jia†‡, Zhiqiang Cao†, Hong Xue†, Yongshen Xu‡ and Shaoyi Jiang*†
pp 3196–3199

Interaction of Self-Assembling β-Sheet Peptides with Phospholipid Monolayers: The Role of Aggregation State, Polarity, Charge and Applied Field
Elisabeth Protopapa, Steven Maude, Amalia Aggeli and Andrew Nelson*
pp 3289–3296

JACS, 131, 5716-6036, 2009

Core Functionalization of Hollow Polymer Nanocapsules
Xiang Liu and Amit Basupp
pp 5718–5719

Photoregulated Release of Caged Anticancer Drugs from Gold Nanoparticles
Sarit S. Agasti, Apiwat Chompoosor, Chang-Cheng You, Partha Ghosh, Chae Kyu Kim and Vincent M. Rotello
pp 5728–5729

Sequential Phosphine-Catalyzed, Nucleophilic Thiol−Ene/Radical-Mediated Thiol−Yne Reactions and the Facile Orthogonal Synthesis of Polyfunctional Materials
Justin W. Chan, Charles E. Hoyle and Andrew B. Lowe
pp 5751–5753

Selective Toxin Sequestrants for the Treatment of Bacterial Infections
Levi S. Simpson, Lyle Burdine, Amal K. Dutta, Andrew P. Feranchak and Thomas Kodadek
pp 5760–5762

JACS, 131, 5364-5714, 2009

Synthesis and Characterization of Organometallic Coordination Polymer Nanoshells of Prussian Blue Using Miniemulsion Periphery Polymerization (MEPP)
Guodong Liang, Junting Xu and Xiaosong Wang
pp 5378–5379

A Direct Route to Cyclic Organic Nanostructures via Ring-Expansion Metathesis Polymerization of a Dendronized Macromonomer
Andrew J. Boydston, Thomas W. Holcombe, David A. Unruh, Jean M. J. Frchet and Robert H. Grubbs
pp 5388–5389

JACS, 131, 4554-5010, 2009

PEG Branched Polymer for Functionalization of Nanomaterials with Ultralong Blood Circulation
Giuseppe Prencipe, Scott M. Tabakman, Kevin Welsher, Zhuang Liu, Andrew P. Goodwin, Li Zhang, Joy Henry and Hongjie Dai
pp 4783–4787

JACS, 131, 4172-4552, 2009

Self-Assembly of Nanostructured Diatom Microshells into Patterned Arrays Assisted by Polyelectrolyte Multilayer Deposition and Inkjet Printing
Wei Wang, Timothy Gutu, Debra K. Gale, Jun Jiao, Gregory L. Rorrer and Chih-hung Chang
pp 4178–4179

Nucleobase-Templated Polymerization: Copying the Chain Length and Polydispersity of Living Polymers into Conjugated Polymers

Pik Kwan Lo and Hanadi F. Sleiman
pp 4182–4183

Synthesis of a Cross-Linked Branched Polymer Network in the Interior of a Protein Cage
Md Joynal Abedin, Lars Liepold, Peter Suci, Mark Young and Trevor Douglas
pp 4346–4354

Stop-Flow Lithography for the Production of Shape-Evolving Degradable Microgel Particles
Dae Kun Hwang, John Oakey, Mehmet Toner, Jeffrey A. Arthur, Kristi S. Anseth, Sunyoung Lee, Adam Zeiger, Krystyn J. Van Vliet and Patrick S. Doyle
pp 4499–4504

Biomacromolecules

Volume 10, Issue 4 (April 09)

Water-Stable Diblock Polystyrene-block-poly(2-vinyl pyridine) and Diblock Polystyrene-block-poly(methyl methacrylate) Cylindrical Patterned Surfaces Inhibit Settlement of Zoospores of the Green Alga Ulva

Claudia M. Grozea^†, Nikhil Gunari^‡, John A. Finlay^§, Daniel Grozea, Maureen E. Callow^§, James A. Callow^§, Zheng-Hong Lu and Gilbert C. Walker*^†

pp 1004–1012

Journal of Polymer Science Part A: Polymer Chemistry

Volume 47 Issue 10 (May 2009)

An efficient synthetic route to well-defined theta-shaped copolymers
Gang-Yin Shi, Cai-Yuan Pan
(p 2620-2630)

Macromolecular Chemistry and Physics

Vol 210, Iss 7, April 09

The Influence of Counterion Type and Temperature on Flory-Huggins Binary Interaction Parameter in Polyelectrolyte Hydrogels
Alexander P. Safronov, Felix A. Blyakhman, Tatyana F. Shklyar, Tatyana V. Terziyan, Marina A. Kostareva, Sergey A. Tchikunov, Gerald H. Pollack p 511-519

Vol 210, Iss 8, April 09

Synthesis and Characterization of Amphiphilic Polyethers Based on Tetrahydrofuran and Glycidol: Antibacterial Assessment
Stefan Theiler, Thomas Hövetborn, Helmut Keul, Martin Möller
p 614-630

Solution Self-Assembly of Core-Labeled Block Random-Copolymers Prepared by Ring Opening Metathesis Polymerization
Martina Sandholzer, Christian Slugovc
p 651-658

Saturday, April 25, 2009

chembiochem, 2009, 10, 959-969

Olefin Metathesis for Site-Selective Protein Modification
Yuya A. Lin, Justin M. Chalker, and Benjamin G. Davis*

minireview

organic letters, 2009, 11 (6), 1261-1264

Well-Defined Silica-Supported Olefin Metathesis Catalysts

Daryl P. Allen, Matthew M. Van Wingerden, and Robert H. Grubbs

organic letters, 2009, 11 (8), 1693-1695

Revised Structure and Synthesis of Celastramycin A, A Potent Innate Immune Suppressor

Haruhisa Kikuchi, Mizuki Sekiya, Yasuhiro Katou, Kazunori
Ueda, Takahiro Kabeya, Shoichiro Kurata, and Yoshiteru Oshima

Thursday, April 2, 2009

Macromol. Rapid. Commun. 10 Years Special Edition w/ lots of great reviews

Enzymatic Polymerization

Porous Polymers

Blockcopolymer Aggregates

Polypeptides

Sulfur Polymers

Tuesday, March 24, 2009

J. Mater. Chem., 2009, 19, 1968 - 1977

An improved injectable polysaccharide hydrogel: modified gellan gum
for long-term cartilage regeneration in vitro

Yihong Gong, Chunming Wang, Ruenn Chai Lai, Kai Su, Feng Zhang and Dong-an Wang*

Monday, March 23, 2009

Biochimica et Biophysica Acta 1788 (2009) 650–659

Peptide induced demixing in PG/PE lipid mixtures: A mechanism for the specificity of
antimicrobial peptides towards bacterial membranes?
Ahmad Arouri, Margitta Dathe, Alfred Blume

J. Mater. Chem., 2009, 19, 1483–1489

Synthesis and photophysical property of well-defined
donor–acceptor diblock copolymer based on regioregular
poly(3-hexylthiophene) and fullerene†

Jea Uk Lee,a Ali Cirpan,b Todd Emrick,b Thomas P. Russellb and Won Ho Jo

JACS, Vol. 131, No. 9

Pulsed-Addition Ring-Opening Metathesis Polymerization: Catalyst-Economical Syntheses of Homopolymers and Block Copolymers

John B. Matson, Scott C. Virgil and Robert H. Grubbs

Metal-Binding Dependent Disruption of Membranes by Designed Helices

Rachel S. Signarvic and William F. DeGrado

JACS, Vol. 131, No. 10

Label-Free, Real-Time Multiplexed DNA Detection Using Fluorescent Conjugated Polymers

Weiming Zheng and Lin He

Synthesis of Copolymers by Alternating ROMP (AROMP)

Airong Song, Kathlyn A. Parker and Nicole S. Sampson

A Nanoscale Adhesion Layer to Promote Cell Attachment on PEEK

T. Joseph Dennes and Jeffrey Schwartz

Assembly of Magnetically Tunable Photonic Crystals in Nonpolar Solvents

Jianping Ge, Le He, James Goebl and Yadong Yin

ACS Nano article 2

Nanodiamond-Polymer Composite Fibers and Coatings

Abstract:

While nanocrystalline diamond is quickly becoming one of the most widely studied nanomaterials, achieving a large fraction of diamond nanoparticles in a polymer coating has been an unresolved problem. In this work, polymer nano- and microfibers containing high loadings of 5 nm diamond particles (up to 80 wt % in polyacrylonitrile and 40% in polyamide 11) have been demonstrated using electrospun nanofibers as a delivery vehicle. The electrospun nanofibers with a high load of nanodiamond in the polymers were fused into thin transparent films, which had high mechanical properties; an improvement of 4 times for the Young’s modulus and 2 times for the hardness was observed already at 20% nanodiamond in polyamide 11. These films can provide UV protection and scratch resistance to a variety of surfaces, especially in applications where a combination of mechanical, thermal, and dielectric properties is required.

ACS Nano article 1

A Mechanical Actuator Driven Electrochemically by Artificial Molecular Muscles

Abstract:

A microcantilever, coated with a monolayer of redox-controllable, bistable [3]rotaxane molecules (artificial molecular muscles), undergoes reversible deflections when subjected to alternating oxidizing and reducing electrochemical potentials. The microcantilever devices were prepared by precoating one surface with a gold film and allowing the palindromic [3]rotaxane molecules to adsorb selectively onto one side of the microcantilevers, utilizing thiol-gold chemistry. An electrochemical cell was employed in the experiments, and deflections were monitored both as a function of (i) the scan rate (≤20 mV s⁻¹) and (ii) the time for potential step experiments at oxidizing (>+0.4 V) and reducing (<+0.2 V) potentials. The different directions and magnitudes of the deflections for the microcantilevers, which were coated with artificial molecular muscles, were compared with (i) data from nominally bare microcantilevers precoated with gold and (ii) those coated with two types of control compounds, namely, dumbbell molecules to simulate the redox activity of the palindromic bistable [3]rotaxane molecules and inactive 1-dodecanethiol molecules. The comparisons demonstrate that the artificial molecular muscles are responsible for the deflections, which can be repeated over many cycles. The microcantilevers deflect in one direction following oxidation and in the opposite direction upon reduction. The

550 nm deflections were calculated to be commensurate with forces per molecule of

650 pN. The thermal relaxation that characterizes the device’s deflection is consistent with the double bistability associated with the palindromic [3]rotaxane and reflects a metastable contracted state. The use of the cooperative forces generated by these self-assembled, nanometer-scale artificial molecular muscles that are electrically wired to an external power supply constitutes a seminal step toward molecular-machine-based nanoelectromechanical systems (NEMS).