Nature materials volume 8 No 2 pg 151

Infection-mimicking materials to program dendritic cells in situ -pp151 - 158

Omar A. Ali, Nathaniel Huebsch, Lan Cao, Glenn Dranoff & David J. Mooney

doi:10.1038/nmat2357

Cancer vaccines developed so far typically rely on cell manipulation techniques in the laboratory followed by re-introduction of the cells into the patient. Now, a polymeric material is shown to program and control the trafficking of immune cellsin situ, resulting in specific and protective anti-tumour properties.