Finding better protein engineering strategies - pp526 - 529
Romas J Kazlauskas & Uwe T Bornscheuer
doi:10.1038/nchembio0809-526
Protein improvement strategies today involve widely varying combinations of rational design with random mutagenesis and screening. To make further progress—defined as making subsequent protein engineering problems easier to solve—protein engineers must critically compare these strategies and eliminate less effective ones.
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