ACS Nano, 2012, 6 (3), pp 2289–2301

Influence of Geometry, Porosity, and Surface Characteristics of Silica Nanoparticles on Acute Toxicity: Their Vasculature Effect and Tolerance Threshold Tian Yu†‡, Khaled Greish†‡, Lawrence D. McGill, Abhijit Ray†‡, and Hamidreza Ghandehari†‡§* †Department of Pharmaceutics and Pharmaceutical Chemistry, ‡Utah Center for Nanomedicine, Nano Institute of Utah, and §Department of Bioengineering, University of Utah, Salt Lake City, Utah 84108, United States, Animal Reference Pathology Division, ARUP Laboratories, Salt Lake City, Utah 84108, United States