Org Biol Chem

Tumor targeting in photodynamic therapy. From glycoconjugated photosensitizers to glycodendrimeric one. Concept, design and properties

Séverine Ballut, Ali Makky, Benoît Chauvin, Jean-Philippe Michel, Athena Kasselouri, Philippe Maillard and Véronique Rosilio

Org. Biomol. Chem., 2012, 10, 4485-4495 

The ligand and base-free Pd-catalyzed oxidative Heck reaction of arylboronic acids and olefins

Peng Sun, Yan Zhu, Hailong Yang, Hong Yan, Linhua Lu, Xiang Zhang and Jincheng Mao

Org. Biomol. Chem., 2012, 10, 4512-4515 

PEGylation of an artificial O₂ and CO receptor: synthesis, characterisation and pharmacokinetic study

Takunori Ueda, Hiroaki Kitagishi and Koji Kano

Org. Biomol. Chem., 2012, 10, 4337-4347

A receptor incorporating OH, NH and CH binding motifs for a fluoride selective chemosensor

Liang Xu, Yongjun Li, Yanwen Yu, Taifeng Liu, Songhua Cheng, Huibiao Liu and Yuliang Li

Org. Biomol. Chem., 2012, 10, 4375-4380 

ACS chem bio

Redesign of Glycopeptide Antibiotics: Back to the Future

Robert C. James, Joshua G. Pierce, Akinori Okano, Jian Xie, and Dale L. Boger

pp 797–804

Bicyclic Peptide Inhibitor Reveals Large Contact Interface with a Protease Target

Alessandro Angelini, Laura Cendron, Shiyu Chen, Jeremy Touati, Greg Winter, Giuseppe Zanotti, and Christian Heinis

pp 817–821

A High-Throughput Screen for the Engineered Production of β-Lactam Antibiotics

Ryan M. Phelan, Benjamin J. DiPardo, and Craig A. Townsend

pp 835–840

Amide Analogues of CD1d Agonists Modulate iNKT-Cell-Mediated Cytokine Production

Justyna Wojno, John-Paul Jukes, Hemza Ghadbane, Dawn Shepherd, Gurdyal S. Besra, Vincenzo Cerundolo, and Liam R. Cox

pp 847–855

Visualization and Quantitative Analysis of G Protein-Coupled Receptor−β-Arrestin Interaction in Single Cells and Specific Organs of Living Mice Using Split Luciferase Complementation

Hideo Takakura, Mitsuru Hattori, Masaki Takeuchi, and Takeaki Ozawa

pp 901–910

Journal of the American Chemical Society, Volume 134, Issue 20, Pages 8289-8728

High-Yielding, Versatile, and Practical [Rh(III)Cp*]-Catalyzed Ortho Bromination and Iodination of Arenes  
Nils Schröder, Joanna Wencel-Delord, and Frank Glorius  
pp 8298–8301

Strained Ruthenium Complexes Are Potent Light-Activated Anticancer Agents  
Brock S. Howerton, David K. Heidary, and Edith C. Glazer  
pp 8324–8327

Fundamental Molecular Design for Precise Control of Thermoresponsiveness of Organic Polymers by Using Ternary Systems  
Shogo Amemori, Kenta Kokado, and Kazuki Sada  
pp 8344–8347

Making Insoluble Polymer Networks Malleable via Olefin Metathesis  
Yi-Xuan Lu, François Tournilhac, Ludwik Leibler, and Zhibin Guan  
pp 8424–8427

Altering the Static Dipole on Surfaces through Chemistry: Molecular Films of Zwitterionic Quinonoids  
Lucie Routaboul, Pierre Braunstein, Jie Xiao, Zhengzheng Zhang, Peter A. Dowben, Guillaume Dalmas, Victor Da Costa, Olivier Félix, Gero Decher, Luis G. Rosa, and Bernard Doudin  
pp 8494–8506

Diffusion Mechanism of Lithium Ion through Basal Plane of Layered Graphene  
Fei Yao, Fethullah Güneş, Huy Quang Ta, Seung Mi Lee, Seung Jin Chae, Kyeu Yoon Sheem, Costel Sorin Cojocaru, Si Shen Xie, and Young Hee Lee  
pp 8646–8654

Journal of the American Chemical Society, Volume 134, Issue 19, Pages 8001-8288

Alkane Lengths Determine Encapsulation Rates and Equilibria  
Wei Jiang, Dariush Ajami, and Julius Rebek, Jr.  
pp 8070–8073

Supramolecular Polymers as Dynamic Multicomponent Cellular Uptake Carriers  
Katja Petkau-Milroy, Michael H. Sonntag, Arthur H. A. M. van Onzen, and Luc Brunsveld  
pp 8086–8089

Nonlinear Optical Molecular Switches as Selective Cation Sensors  
Benoît Champagne, Aurélie Plaquet, Jean-Luc Pozzo, Vincent Rodriguez, and Frédéric Castet pp 8101–8103

Journal of the American Chemical Society, Volume 134, Issue 18, Pages 7575-8000

Pendant Polymer:Amino-β-Cyclodextrin:siRNA Guest:Host Nanoparticles as Efficient Vectors for Gene Silencing
Aditya Kulkarni, Kyle DeFrees, Seok-Hee Hyun, and David H. Thompson
pp 7596–7599

Coordination-Network-Based Ionic Plastic Crystal for Anhydrous Proton Conductivity
Satoshi Horike, Daiki Umeyama, Munehiro Inukai, Tomoya Itakura, and Susumu Kitagawa
pp 7612–7615

Phosphatidylserine Reversibly Binds Cu2+ with Extremely High Affinity
Christopher F. Monson, Xiao Cong, Aaron D. Robison, Hudson P. Pace, Chunming Liu, Matthew F. Poyton, and Paul S. Cremer
pp 7773–7779

Three Distinct Water Structures at a Zwitterionic Lipid/Water Interface Revealed by Heterodyne-Detected Vibrational Sum Frequency Generation
Jahur A. Mondal, Satoshi Nihonyanagi, Shoichi Yamaguchi, and Tahei Tahara
pp 7842–7850

Decomposition Pathways of Z-Selective Ruthenium Metathesis Catalysts
Myles B. Herbert, Yu Lan, Benjamin K. Keitz, Peng Liu, Koji Endo, Michael W. Day, K. N. Houk, and Robert H. Grubbs
pp 7861–7866

Rutile-TiO2 Nanocoating for a High-Rate Li4Ti5O12 Anode of a Lithium-Ion Battery
Yong-Qing Wang, Lin Gu, Yu-Guo Guo, Hong Li, Xiao-Qing He, Susumu Tsukimoto, Yuichi Ikuhara, and Li-Jun Wan
pp 7874–7879

Synthesis of Oligo(thiophene)-Coated Star-Shaped ROMP Polymers: Unique Emission Properties by the Precise Integration of Functionality
Kenji Takamizu and Kotohiro Nomura
pp 7892–7895

Li–O2 Battery with a Dimethylformamide Electrolyte
Yuhui Chen, Stefan A. Freunberger, Zhangquan Peng, Fanny Bardé, and Peter G. Bruce
pp 7952–7957

Journal of the American Chemical Society, Volume 134, Issue 17, Pages 7195-7574

Highly Efficient (R-X-R)-Type Carbamates as Molecular Transporters for Cellular Delivery
Kiran M. Patil, Rangeetha J. Naik, Rajpal, Moneesha Fernandes, Munia Ganguli, and Vaijayanti A. Kumar
pp 7196–7199

Fullerene/Cobalt Porphyrin Hybrid Nanosheets with Ambipolar Charge Transporting Characteristics Takatsugu Wakahara, Pasquale D’Angelo, Kun’ichi Miyazawa, Yoshihiro Nemoto, Osamu Ito, Nobutaka Tanigaki, Donal D.C. Bradley, and Thomas D. Anthopoulos
pp 7204–7206

Fast Tandem Ring-Opening/Ring-Closing Metathesis Polymerization from a Monomer Containing Cyclohexene and Terminal Alkyne
Hyeon Park and Tae-Lim Choi
pp 7270–7273

Stereoselectivity in Metallocene-Catalyzed Coordination Polymerization of Renewable Methylene Butyrolactones: From Stereo-random to Stereo-perfect Polymers
Xia Chen, Lucia Caporaso, Luigi Cavallo, and Eugene Y.-X. Chen
pp 7278–7281

Efficient Alkyl Ether Synthesis via Palladium-Catalyzed, Picolinamide-Directed Alkoxylation of Unactivated C(sp3)–H and C(sp2)–H Bonds at Remote Positions
Shu-Yu Zhang, Gang He, Yingsheng Zhao, Kiwan Wright, William A. Nack, and Gong Chen
pp 7313–7316

Reversible Changes in Solution pH Resulting from Changes in Thermoresponsive Polymer Solubility Yanfei Yang, Alexander J. Mijalis, Hui Fu, Cynthia Agosto, Kristine J. Tan, James D. Batteas, and David E. Bergbreiter
pp 7378–7383

Reductively Responsive siRNA-Conjugated Hydrogel Nanoparticles for Gene Silencing
Stuart S. Dunn, Shaomin Tian, Steven Blake, Jin Wang, Ashley L. Galloway, Andrew Murphy, Patrick D. Pohlhaus, Jason P. Rolland, Mary E. Napier, and Joseph M. DeSimone
pp 7423–7430

pH Control of Intramolecular Energy Transfer and Oxygen Quenching in Ru(II) Complexes Having Coupled Electronic Excited States
Tod A. Grusenmeyer, Jin Chen, Yuhuan Jin, Jonathan Nguyen, Jeffrey J. Rack, and Russell H. Schmehl
pp 7497–7506

Advanced Drug Delivery Reviews, Volume 64, Issue 7, Pages 589-706

Theme: Delivery of Therapeutics to the Central Nervous System

Delivery of therapeutics to the central nervous system
James J. Chambers
Volume 64, Issue 7, 15 May 2012, Pages 589

Challenges in drug delivery to tumors of the central nervous system: An overview of pharmacological and surgical considerations
Laura P. Serwer, C. David James
Volume 64, Issue 7, 15 May 2012, Pages 590–597

Guided delivery of adeno-associated viral vectors into the primate brain
Ernesto A. Salegio, Lluis Samaranch, Adrian P. Kells, John Forsayeth, Krystof Bankiewicz
Volume 64, Issue 7, 15 May 2012, Pages 598–604

Nanomaterial-mediated CNS delivery of diagnostic and therapeutic agents
Laura Biddlestone-Thorpe, Nicola Marchi, Kathy Guo, Chaitali Ghosh, Damir Janigro, Kristoffer Valerie, Hu Yang
Volume 64, Issue 7, 15 May 2012, Pages 605–613

Modern methods for delivery of drugs across the blood–brain barrier
Yan Chen, Lihong Liu
Volume 64, Issue 7, 15 May 2012, Pages 640–665

Prodrug approaches to reduce hyperexcitation in the CNS
Devaiah Vytla, Rosamund E. Combs-Bachmann, Amanda M. Hussey, Stephen T. McCarron, Devon S. McCarthy, James J. Chambers
Volume 64, Issue 7, 15 May 2012, Pages 666–685

Polymeric nanoparticles for drug delivery to the central nervous system
Toral Patel, Jiangbing Zhou, Joseph M. Piepmeier, W. Mark Saltzman
Volume 64, Issue 7, 15 May 2012, Pages 701–705

 

 

Advanced Drug Delivery Reviews, Volume 64, Issue 6, Pages 479-588

Theme: Advances in Oral Drug Delivery: Improved Biovailability of Poorly Absorbed Drugs by Tissue and Cellular Optimization

Advances in oral drug delivery: improved bioavailability of poorly absorbed drugs by tissue and cellular optimization
Mariko Morishita, Nicholas A. Peppas
Volume 64, Issue 6, 1 May 2012, Pages 479

Modification of physicochemical characteristics of active pharmaceutical ingredients and application of supersaturatable dosage forms for improving bioavailability of poorly absorbed drugs
Kohsaku Kawakami
Volume 64, Issue 6, 1 May 2012, Pages 480–495

Oral biodrug delivery using cell-penetrating peptide
El-Sayed Khafagy, Mariko Morishita
Volume 64, Issue 6, 1 May 2012, Pages 531–539

Transepithelial transport and toxicity of PAMAM dendrimers: Implications for oral drug delivery
S. Sadekar, H. Ghandehari
Volume 64, Issue 6, 1 May 2012, Pages 571–588

Advanced Drug Delivery Reviews, Volume 64, Issue 5, Pages 383-478

Theme: The role of thermal analysis and calorimetry in pharmaceutical design and development

Thermal analysis and calorimetry
Simon Gaisford
Volume 64, Issue 5, April 2012, Pages 383

Pharmaceutical applications of dynamic mechanical thermal analysis
David S. Jones, Yiwei Tian, Osama Abu-Diak, Gavin P. Andrews
Volume 64, Issue 5, April 2012, Pages 440–448

Advanced Drug Delivery Reviews, Volume 64, Issue 4, Pages 295-382

Computational and Visualization approaches in Respiratory Delivery

Computational and visualization approaches in respiratory delivery 

Paul M. Young, Daniela Traini
Volume 64, Issue 4, 30 March 2012, Pages 295

Structural modelling and dynamics of proteins for insights into drug interactions
Tim Werner, Michael B. Morris, Siavoush Dastmalchi, W. Bret Church

Volume 64, Issue 4, 30 March 2012, Pages 323–343

 

Polym. Chem., 2012,3, 1647-1658

Thiol-Michael coupling chemistry: facile access to a library of functional exo-7-oxanorbornenes and their ring-opening metathesis (co)polymerization Centre for Advanced Macromolecular Design (CAMD), School of Chemical Engineering, The University of New South Wales, Kensington, Sydney, New South Wales 2052, Australia

Polym. Chem., 2012,3, 1408-1417

Thermoresponsive polymer brush-functionalized magnetic manganite nanoparticles for remotely triggered drug release aCNRS, Univ. Bordeaux, LCPO, UMR 5629, F-33600, Pessac, France bCNRS, Univ. Bordeaux, ICMCB, UPR 9048, F-33600, Pessac, France

Polym. Chem., 2012,3, 1539-1545

Biodegradable, pH-sensitive P(CL-Pluronic-CL-co-MAA-MEG) hydrogel for 5-aminosalicylic acid delivery Faculty of Pharmacy, School of Medicine, Xi' an Jiaotong University, Xi' an, 710061, China

Chemistry: A European Journal, vol. 18 issue 22

Chem. Eur. J. 2012, 18, 6895 – 6906.  StereoselectiveSynthesis of α- and β-Glycofuranosyl Amides by Traceless Ligation ofGlycofuranosyl Azides.

Advanced Drug Delivery Reviews, Volume 64, Issue 3, Pages 217-294

Theme: Lactose as a Carrier for Inhalation Products

Lactose as a carrier for inhalation products: breathing new life into an old carrier
Chris Marriott Henderik W. Frijlink

Volume 64, Issue 3, 15 March 2012, Pages 217–219

Chemistry: A European Journal, vol. 18 issue 21

Chem. Eur. J. 2012, 18, 6465 – 6469.  Ruthenium–AmidoComplexes: Synthesis, Structure, and Catalytic Activity in Olefin Metathesis.

Chem. Eur. J. 2012, 18, 6528 – 6541.  Design,Synthesis and Biological Evaluation of Potent Azadipeptide Nitrile Inhibitorsand Activity-Based Probes as Promising Anti-Trypanosoma brucei Agents.

 

Advanced Drug Delivery Reviews, Volume 64, Issue 2, Pages 127-216

Theme: Biological Interactions of Nanoparticles

Toxicology of nanoparticles

Andreas Elsaesser, C. Vyvyan Howard
Volume 64, Issue 2, February 2012, Pages 129–137

Quantum dots to tail single bio-molecules inside living cells

Paolo Pierobon, Giovanni Cappello
Volume 64, Issue 2, February 2012, Pages 167–178

Physico-chemical parameters that govern nanoparticles fate also dictate rules for their molecular evolution

Sandrine Dufort, Lucie Sancey, Jean-Luc Coll
Volume 64, Issue 2, February 2012, Pages 179–189

ACS Nano, 2012, 6 (5), pp 4279–4287

Surface Charge-Switching Polymeric Nanoparticles for Bacterial Cell Wall-Targeted Delivery of Antibiotics Aleksandar F. Radovic-Moreno†‡, Timothy K. Lu§, Vlad A. Puscasu‡, Christopher J. Yoon‡§, Robert Langer†‡*, and Omid C. Farokhzad* † Harvard-MIT Division of Health Sciences & Technology, Cambridge, Massachusetts 02139, United States ‡ Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States § Synthetic Biology Group, Department of Electrical Engineering & Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States Laboratory of Nanomedicine and Biomaterials, Department of Anesthesiology, Brigham & Women’s Hospital, Harvard Medical School, Boston, Massachusetts 02115, United States

ACS Nano, 2012, 6 (5), pp 4157–4168

Enhanced Delivery of Chemotherapy to Tumors Using a Multicomponent Nanochain with Radio-Frequency-Tunable Drug Release Pubudu M. Peiris†‡§, Lisa Bauer§, Randall Toy†§, Emily Tran†§, Jenna Pansky†§, Elizabeth Doolittle†§, Erik Schmidt†§, Elliott Hayden†§, Aaron Mayer†§, Ruth A. Keri¶, Mark A. Griswold‡§, and Efstathios Karathanasis†‡§¶* †Department of Biomedical Engineering, ‡Department of Radiology, §Case Center for Imaging Research, Department of Physics, Department of Pharmacology, and ¶Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio 44106, United States

ACS Nano, 2012, 6 (5), pp 4083–4093

Effects of Serum Adsorption on Cellular Uptake Profile and Consequent Impact of Titanium Dioxide Nanoparticles on Human Lung Cell Lines Roslyn Tedja†, May Lim†*, Rose Amal†, and Christopher Marquis‡* † ARC Centre of Excellence for Functional Nanomaterials, School of Chemical Engineering, The University of New South Wales, Sydney NSW 2052, Australia ‡ School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney NSW 2052, Australia

ACS Nano, 2012, 6 (5), pp 3974–3981

Pattern Recognition of Cancer Cells Using Aptamer-Conjugated Magnetic Nanoparticles Suwussa Bamrungsap†, Tao Chen†, Mohammed Ibrahim Shukoor†, Zhuo Chen‡, Kwame Sefah†, Yan Chen†‡, and Weihong Tan†‡* † Center for Research at Bio/nano Interface, Department of Chemistry and Department of Physiology and Functional Genomics, Shands Cancer Center, UF Genetics Institute and McKnight Brain Institute, University of Florida, Gainesville, Florida 32611-7200, United States, ‡ State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, College of Biology and College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, People's Republic of China

ACS Nano, 2012, 6 (5), pp 3954–3966

Synthesis and Biological Response of Size-Specific, Monodisperse Drug–Silica Nanoconjugates Li Tang†, Timothy M. Fan‡, Luke B. Borst§, and Jianjun Cheng†* †Department of Materials Science and Engineering and ‡Department of Veterinary Clinical Medicine, University of Illinois at Urbana—Champaign, Urbana, Illinois 61801, United States § Department of Population Health and Pathobiology, North Carolina State University, Raleigh, North Carolina 27606, United States

ACS Nano, 2012, 6 (5), pp 3925–3934

Shape-Programmed Folding of Stimuli-Responsive Polymer Bilayers Georgi Stoychev†‡, Svetlana Zakharchenko†‡, Sébastien Turcaud§, John W. C. Dunlop§, and Leonid Ionov†* † Leibniz Institute of Polymer Research Dresden, Hohe Straße 6, D-01069 Dresden, Germany and Department of Biomaterials ‡ Technische Universität Dresden, Physical Chemistry of Polymer Materials, 01062 Dresden, Germany § Max Planck Institute of Colloids and Interfaces, Am Mühlenberg 1, D-14424, Potsdam, Germany

Nano Lett., 2012, 12 (5), pp 2520–2523

An Integrated Power Pack of Dye-Sensitized Solar Cell and Li Battery Based on Double-Sided TiO2 Nanotube Arrays Wenxi Guo†‡, Xinyu Xue†§, Sihong Wang†, Changjian Lin‡, and Zhong Lin Wang*† † School of Material Science and Engineering, Georgia Institute of Technology, Georgia 30332, United States ‡ State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China § College of Sciences, Northeastern University, Shenyang 110004, China Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing, China

Nano Lett., 2012, 12 (5), pp 2233–2237

Controlled Dissolution of Polystyrene Nanobeads: Transition from Liquid Electrolyte to Gel Electrolyte Kun Seok Lee†, Yongseok Jun‡, and Jong Hyeok Park*† † School of Chemical Engineering and SAINT, Sungkyunkwan University, Suwon 440-746, Republic of Korea ‡ Interdisciplinary School of Green Energy, KIER-UNIST ACE, UNIST, Ulsan 689-798, Republic of Korea

Chemistry - A European Journal, vol 18 issue 20

Chem. Eur. J. 2012, 18, 6195 – 6207 _ 2012.  Cyclic RGD PeptidomimeticsContaining Bifunctional Diketopiperazine Scaffolds as New Potent IntegrinLigands.

 Chem. Eur. J. 2012, 18, 6230 – 6237.  Ion-Pair Recognition by a Heteroditopic Triazole-ContainingReceptor.

Chem. Eur. J. 2012, 18, 6238 – 6249.  ThiolsScreened by the Neocarzinostatin Protein for Preserving or Detoxifying itsBound Enediyne Antibiotic.