Antimicrobial Agents and Chemotherapy, October 2009, p. 4283-4291, Vol. 53, No. 10

Novel Broad-Spectrum Bis-(Imidazolinylindole) Derivatives with Potent Antibacterial Activities against Antibiotic-Resistant Strains

Rekha G. Panchal,^1* Ricky L. Ulrich,¹ Douglas Lane,² Michelle M. Butler,³ Chad Houseweart,³ Timothy Opperman,³ John D. Williams,³ Norton P. Peet,³ Donald T. Moir,³ Tam Nguyen,² Rick Gussio,⁴ Terry Bowlin,³ and Sina Bavari^1*

United States Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Fort Detrick, Frederick, Maryland 21702-5011,¹ Target Structure Based Drug Discovery Group, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland 21702-1201,² Microbiotix Inc., One Innovation Dr., Worcester, Massachusetts 01605,³Target Structure Based Drug Discovery Group, Information Technology Branch, Developmental Therapeutic Program, National Cancer Institute, Frederick, Maryland 21702-1201⁴