ACS Nano, 2012, 6 (5), pp 4279–4287

Surface Charge-Switching Polymeric Nanoparticles for Bacterial Cell Wall-Targeted Delivery of Antibiotics Aleksandar F. Radovic-Moreno†‡, Timothy K. Lu§, Vlad A. Puscasu‡, Christopher J. Yoon‡§, Robert Langer†‡*, and Omid C. Farokhzad* † Harvard-MIT Division of Health Sciences & Technology, Cambridge, Massachusetts 02139, United States ‡ Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States § Synthetic Biology Group, Department of Electrical Engineering & Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States Laboratory of Nanomedicine and Biomaterials, Department of Anesthesiology, Brigham & Women’s Hospital, Harvard Medical School, Boston, Massachusetts 02115, United States