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Monday, August 10, 2009

Antimicrobial Agents and Chemotherapy, August 2009, p. 3538-3540, Vol. 53, No. 8

Synergistic Interaction between Silver Nanoparticles and Membrane-Permeabilizing Antimicrobial Peptides

Silver nanoparticles, as well as antimicrobial peptides (AMPs), can be used to fight infectious diseases. Since AMPs are known to permeabilize bacterial membranes and might therefore help silver nanoparticles to access internal target sites, we investigated their combined activities and showed synergistic effects betweenpolymyxin B and silver nanoparticles for gram-negative bacteria.

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