Nano Lett., 2012, 12 (7), pp 3587–3591

Mass Production and Size Control of Lipid–Polymer Hybrid Nanoparticles through Controlled Microvortices YongTae Kim†, Bomy Lee Chung†‡, Mingming Ma†, Willem J. M. Mulder, Zahi A. Fayad, Omid C. Farokhzad, and Robert Langer*†‡§ †David H. Koch Institute for Integrative Cancer Research, ‡Department of Chemical Engineering, and §Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States Translational and Molecular Imaging Institute, Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1234, New York, 10029, United States Department of Anesthesiology, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts 02115, United States