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Tuesday, June 7, 2011

ACS Nano, 2011, 5 (5), pp 3493–3505

Influence of Nano-Carrier Architecture on in Vitro siRNA Delivery Performance and in Vivo Biodistribution: Polyplexes vs Micelleplexes

Dana J. Gary†, Hoyoung Lee†, Rahul Sharma†, Jae-Sung Lee†, Youngwook Kim‡, Zheng Yun Cui‡, Di Jia§, Valorie D. Bowman§, Paul R. Chipman§, Lei Wan, Yi Zou, Guangzhao Mao, Keunchil Park‡, Brittney-Shea Herbert#, Stephen F. Konieczny§, and You-Yeon Won†*
† School of Chemical Engineering, Purdue University, West Lafayette, Indiana 47907, United States
‡ Medical Nanoelement Development Center, Samsung Medical Center, Seoul, Korea 135-710
§ Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907, United States
Department of Chemical Engineering and Materials Science, Wayne State University, Detroit, Michigan 48202, United States
Department of Hematology and Oncology, Samsung Medical Center, Seoul, Korea 135-710
# Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana 46202, United States

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