ACS Nano, 2012, 6 (3), pp 2174–2188

Delivery of Small Interfering RNA by Peptide-Targeted Mesoporous Silica Nanoparticle-Supported Lipid Bilayers Carlee E. Ashley†*, Eric C. Carnes‡§, Katharine E. Epler§, David P. Padilla§, Genevieve K. Phillips, Robert E. Castillo§, Dan C. Wilkinson§, Brian S. Wilkinson§, Cameron A. Burgard§, Robin M. Kalinich, Jason L. Townson§, Bryce Chackerian, Cheryl L. Willman#, David S. Peabody, Walker Wharton#, and C. Jeffrey Brinker‡§* † Biotechnology and Bioengineering Department, Sandia National Laboratories, Livermore, California 94551-0969, United States ‡ Department of Chemical and Nuclear Engineering, University of New Mexico, Albuquerque, New Mexico 87131, United States § Center for Micro-Engineered Materials, University of New Mexico, Albuquerque, New Mexico 87131, United States Cancer Research and Treatment Center, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, United States Ceramic Processing and Inorganic Materials Department, Sandia National Laboratories, Albuquerque, New Mexico 87185-1349, United States # Department of Pathology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, United States Department of Molecular Genetics and Microbiology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, United States Self-Assembled Materials Department, Sandia National Laboratories, Albuquerque, New Mexico 87185-1349, United States